| Gene info: |
A DC-SIGN homologue (termed DC-SIGNR, DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR are known to exisit, DCs also amplify the amount of virus and extend the duration of viral infectivity, HIV-2 and SIV bind to DCs via DC-SIGN, ICAM-3 is the natural ligand for DC-SIGN, L-SIGN, Multiple strains of HIV-1, The expression of DC-SIGN was found in mucosal tissues including placenta, and DC-SIGN2) was identified recently, and rectum, small intestine, where DCs hand over HIV to CD4+ T lymphocytes, DC-SIGN Monoclonal Antibody: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes |
| Gene names: |
CLEC4L, DC-SIGN, DC-SIGN1, DC-SIGN Antibody [8B6] : CDSIGN |
| Antibodie's label: |
unlabelled serum |
| Purity: |
DC-SIGN Monoclonal Antibody is immunoaffinity chromotography purified IgG |
| Ab raised in: |
Mouse |
| Type: |
Monoclonal |
| Monoclonal: |
8B6 |
| Antigen: |
A recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN |
| Immuno application: |
Western Blot, immuno-histo-chemistry, ELISA |
| Antibody advice: |
DC-SIGN antibody can be used for detection of DC-SIGN in Western Blot at 1 - 2 mg/mL and in immunohistochemistry at 5 - 10 mg/mL |
| Suspention, pH, azide: |
02% sodium azide, DC-SIGN Monoclonal Antibody is supplied in PBS containing 0 |
| Keep at: |
stable for one year, DC-SIGN monoclonal antibody can be stored at -20 grades C |
| Works with: |
Human |
| Omim nr: |
46396012 |
| Ncbi nr: |
Q9NNX6 |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
30835 |
| GENE symbol: |
CD209 |
| Antigene name: |
CD209 molecule |
| Source: |
Homo sapiens |
| Protein nr: |
Q9NNX6 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
DC-SIGN [8B6] |
| Short name: |
anti-DC-SIGN Antibody [8B6] |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-DC-SIGN (Antibody to) [8B6] |
| Alternative technique: |
antibodies |
| Identity: |
1641 |
| Gene: |
CD209 |
More about : CD209 |
| Long gene name: |
CD209 molecule |
| Synonyms gene name: |
CD209 antigen |
| Synonyms: |
DC-SIGN CDSIGN DC-SIGN1 CLEC4L |
| Locus: |
19p13, 2 |
| Discovery year: |
2000-07-19 |
| GenBank acession: |
M98457 |
| Entrez gene record: |
30835 |
| Pubmed identfication: |
1518869 |
| RefSeq identity: |
NM_021155 |
| Classification: |
CD molecules Scavenger receptors C-type lectin domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000182530 |