| Also known as: |
SIGN-R1 |
| Other names: |
CD209 antigen-like protein A, CD209 antigen-like protein A, CD209a antigen, Dendritic cell-specific ICAM-3-grabbing non-integrin, dendritic cell-specific ICAM-3-grabbing non-integrin, CD209 antigen-like protein A |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SIGN-R1 |
| Other gene names: |
CD209, CDSIGN, CIRE, Cd209a, Cire, DC-SIGN, DC-SIGN, DC-SIGN1, Dcsign, SIGN-R1, SIGNR5, Cd209a |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgM |
| Clone: |
ER-TR9 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Antibodies, L-SIGN, Like many C-type lectins, Mouse SIGN-R1 is specifically expressed on marginal zone macrophages in the spleen, SIGN-R1 functions as a pathogen recognition receptor <, SIGN-R1 has not been detected on murine dendritic cell populations, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a C-type lectin that has been identified as a murine homologue of the human DC-SIGN related molecule, and at lower levels on liver sinusoidal endothelial cells, and plays an important role in defence against pathogens, are reported to block the uptake of neutral polysaccharides by macrophages, medullary and subcapsular sinus macrophages in the lymph nodes, produced by clone ER-TR9, /I>, I>, SIGN-R1 This item recognises mouse SIGN-R1, in vivo< |
| Form/Appearance: |
Biotin (Purified IgM conjugated to Biotin - liquid) |
| Concentration: |
1 miligram per 1 mililiter, IgM concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of dispatch, or at -20 degree if preferred, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation: |
Biotinylated |
| Gene target: |
SIGN-R1: |
| Short name: |
RAT ANTI MOUSE SIGN-R1: Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
Biotin |
| Alternative name: |
RAT antibody to MOUSE SIGN-R1:biotinilated (Antibody to) |
| Alternative technique: |
antibodies |