| Also known as: |
SQSTM1 |
| Other names: |
EBI3-associated protein of 60 kDa, EBI3-associated protein of 60 kDa, EBI3-associated protein p60, EBIAP, EBIAP, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Sequestosome-1, Ubiquitin-binding protein p62, oxidative stress induced like, p60, phosphotyrosine independent ligand for the Lck SH2 domain p62, phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, sequestosome 1, sequestosome-1, ubiquitin-binding protein p62, sequestosome-1 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SQSTM1 |
| Other gene names: |
A170, EBIAP, ORCA, OSIL, OSIL, PDB3, SQSTM1, ZIP3, p60, p60, p62, p62B, SQSTM1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
6A7 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
SQSTM1 antibody was purified by affinity chromatography |
| Form/Appearance: |
50% glycerol and 0, containing 1% BSA, pH 7, 02% sodium azide, 3, Supplied in PBS buffer |
| Concentration: |
500 ug-1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies, Long term storage should be done after aliquoting and at -20°, thus reducing their activity, C, For shorter periods of time keep the antibody at +4 degrees Celsius |
| Tested applications:: |
Immunofluorescence (IF), Western Blot (WB), Flow Cytometry (FC) |
| French translation: |
anticorps |
| Gene target: |
SQSTM1 |
| Short name: |
SQSTM1 antibody |
| Alternative name: |
sequestosome 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
A170 and OSIL and p60 and p62 and p62B and PDB3 and ZIP3, BT, K63-linked polyubiquitin binding, SQSTM1 and IDBG-61811 and ENSG00000161011 and 8878, Sqstm1 and IDBG-168358 and ENSMUSG00000015837 and 18412, nuclei, this GO :0000407 and pre-autopha this GO somal structure and cellular component this GO :0000932 and cytoplasmic mRNA processing body and cellular component this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002376 and immune system process and biological process this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005776 and autophagic vacuole and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0006914 and autophagy and biological process this GO :0006950 and response to stress and biological process this GO :0008104 and protein localization and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016197 and endosomal transport and biological process this GO :0016234 and inclusion body and cellular component this GO :0016235 and aggresome and cellular component this GO :0016236 and macroautophagy and biological process this GO :0016239 and positive regulation of macroautophagy and biological process this GO :0016605 and PML body and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0030154 and cell differentiation and biological process this GO :0030971 and receptor tyrosine kinase binding and molecular function this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0035556 and intracellular signal transduction and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043122 and regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043130 and ubiquitin binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046578 and regulation of Ras protein signal transduction and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070530 and K63-linked polyubiquitin binding and molecular function this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004674 : protein serine/threonine kinase activity and also this GO :0005080 : protein kinase C binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0019901 : protein kinase binding and also this GO :0030971 : receptor tyrosine kinase binding and also this GO :0042169 : SH2 domain binding and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043130 : ubiquitin binding and also this GO :0070530 : K63-linked polyubiquitin binding, this GO :0005080 : protein kinase C binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0019901 : protein kinase binding, this GO :0030971 : receptor tyrosine kinase binding, this GO :0042169 : SH2 domain binding, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0043130 : ubiquitin binding, this GO :0070530 : K63-linked polyubiquitin binding, 105440 and IDBG-640935 and ENSBTAG00000015591 and 338045, sequestosome 1 |
| Identity: |
11280 |
| Gene: |
SQSTM1 |
More about : SQSTM1 |
| Long gene name: |
sequestosome 1 |
| Synonyms gene: |
PDB3 OSIL |
| Synonyms gene name: |
Paget disease of bone 3 oxidative stress induced like |
| Synonyms: |
p62 p60 p62B A170 |
| Locus: |
5q35, 3 |
| Discovery year: |
2000-06-13 |
| GenBank acession: |
U46751 |
| Entrez gene record: |
8878 |
| Pubmed identfication: |
8650207 8551575 |
| Classification: |
Zinc fingers ZZ-type |
| Havana BLAST/BLAT: |
OTTHUMG00000150643 |