| Also known as: |
LRP5/6 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
LRP5/6 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b kappa |
| Clone: |
1A12 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
LRP 5/6 antibody was purified by affinity chromatography |
| Form/Appearance: |
0, 0, 25% glycerol, and 0, 0), 01% sodium azide, 15 M NaCl, 5% BSA, Supplied in 10 mM Tris-glycine (pH 7 |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies, Long term storage should be done after aliquoting and at -20°, thus reducing their activity, C, For shorter periods of time keep the antibody at +4 degrees Celsius |
| Tested applications:: |
Western Blot (WB) |
| French translation: |
anticorps |
| Gene target: |
LRP5/6 |
| Short name: |
LRP5/6 antibody |
| Alternative name: |
low density lipoprotein receptor-related protein 5/6 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BMND1 and EVR1 and EVR4 and HBM and LR3 and LRP-5 and LRP7 and OPPG and OPS and OPTA1 and VBCH2, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046849 and bone remodeling and biological process this GO :0046850 and regulation of bone remodeling and biological process this GO :0048539 and bone marrow development and biological process this GO :0048596 and embryonic camera-type eye morphogenesis and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0060033 and anatomical structure regression and biological process this GO :0060042 and retina morphogenesis in camera-type eye and biological process this GO :0060059 and embryonic retina morphogenesis in camera-type eye and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060348 and bone development and biological process this GO :0060349 and bone morphogenesis and biological process this GO :0060444 and branching involved in mammary gland duct morphogenesis and biological process this GO :0060603 and mammary gland duct morphogenesis and biological process this GO :0060612 and adipose tissue development and biological process this GO :0060764 and cell-cell signaling involved in mammary gland development and biological process this GO :0060828 and regulation of canonical Wnt signaling pathway and biological process this GO :0061178 and regulation of insulin secretion involved in cellular response to glucose stimulus and biological process this GO :0061299 and retina vasculature morphogenesis in camera-type eye and biological process this GO :0061304 and retinal blood vessel morphogenesis and biological process this GO :0071901 and negative regulation of protein serine/threonine kinase activity and biological process this GO :1902262 and apoptotic process involved in patterning of blood vessels and biological process, LRP5 and IDBG-61383 and ENSG00000162337 and 4041, LRP5 and IDBG-644859 and ENSBTAG00000005903 and 534450, Lrp5 and IDBG-128306 and ENSMUSG00000024913 and 16973, Plasma membranes, Wnt-activated receptor activity, this GO :0001702 and gastrulation with mouth forming second and biological process this GO :0001944 and vasculature development and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0002076 and osteoblast development and biological process this GO :0005515 and protein binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006007 and glucose catabolic process and biological process this GO :0006897 and endocytosis and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016055 and Wnt signaling pathway and biological process this GO :0017147 and Wnt-protein binding and molecular function this GO :0030326 and embryonic limb morphogenesis and biological process this GO :0033690 and positive regulation of osteoblast proliferation and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0035108 and limb morphogenesis and biological process this GO :0035426 and extracellular matrix-cell signaling and biological process this GO :0042074 and cell migration involved in gastrulation and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0042733 and embryonic digit morphogenesis and biological process this GO :0042813 and Wnt-activated receptor activity and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043235 and receptor complex and cellular component this GO :0043434 and response to peptide hormone and biological process this GO :0044332 and Wnt signaling pathway involved in dorsal/ventral axis specification and biological process this GO :0045600 and positive regulation of fat cell differentiation and biological process this GO :0045668 and negative regulation of osteoblast differentiation and biological process this GO :0045840 and positive regulation of mitosis and biological process this GO :0045893 and positive regulation of transcription, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0015026 : coreceptor activity and also this GO :0017147 : Wnt-protein binding and also this GO :0042813 : Wnt-activated receptor activity, this GO :0015026 : coreceptor activity, this GO :0017147 : Wnt-protein binding, this GO :0042813 : Wnt-activated receptor activity, low density lipoprotein receptor-related protein 5 |
| Identity: |
6697 |
| Gene: |
LRP5 |
More about : LRP5 |
| Long gene name: |
LDL receptor related protein 5 |
| Synonyms gene: |
LRP7 OPPG EVR1 |
| Synonyms gene name: |
osteoporosis pseudoglioma syndrome exudative vitreoretinopathy 1 low density lipoprotein receptor-related protein 5 |
| Synonyms: |
LR3 BMND1 HBM OPS OPTA1 VBCH2 EVR4 |
| Locus: |
11q13, 2 |
| Discovery year: |
1998-04-07 |
| GenBank acession: |
AF064548 |
| Entrez gene record: |
4041 |
| Pubmed identfication: |
9714764 10049586 |
| RefSeq identity: |
NM_002335 |
| Classification: |
Low density lipoprotein receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000167570 |
| Locus Specific Databases: |
LOVD - Leiden Open Variation Database |