| Also known as: |
CCM2 |
| Other names: |
Cerebral cavernous malformations 2 protein, Malcavernin, cerebral cavernous malformation 2, cerebral cavernous malformations 2 protein, malcavernin, malcavernin isoform 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CCM2 |
| Other gene names: |
C7orf22, C7orf22, CCM2, OSM, PP10187, CCM2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
2 E4 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
CCM2 antibody was purified by affinity chromatography |
| Form/Appearance: |
50% glycerol and 0, containing 1% BSA, pH 7, 02% sodium azide, 3, Supplied in PBS buffer |
| Concentration: |
500 ug-1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies, Long term storage should be done after aliquoting and at -20°, thus reducing their activity, C, For shorter periods of time keep the antibody at +4 degrees Celsius |
| Tested applications:: |
Immunohistochemistry (IHC), Western Blot (WB), Immunofluorescence (IF) |
| French translation: |
anticorps |
| Gene target: |
CCM2 |
| Short name: |
CCM2 antibody |
| Alternative name: |
cerebral cavernous malformation 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CCM2 and IDBG-15466 and ENSG00000136280 and 83605, CCM2 and IDBG-634072 and ENSBTAG00000008090 and 506450, Ccm2 and IDBG-148293 and ENSMUSG00000000378 and 216527, Cytoplasm, protein binding, this GO :0001568 and blood vessel development and biological process this GO :0001570 and vasculogenesis and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001885 and endothelial cell development and biological process this GO :0001944 and vasculature development and biological process this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007507 and heart development and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0043234 and protein complex and cellular component this GO :0045216 and cell-cell junction organization and biological process this GO :0048839 and inner ear development and biological process this GO :0048845 and venous blood vessel morphogenesis and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0060039 and pericardium development and biological process this GO :0060837 and blood vessel endothelial cell differentiation and biological process this GO :0061154 and endothelial tube morphogenesis and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, cerebral cavernous malformation 2 |
| Identity: |
21708 |
| Gene: |
CCM2 |
More about : CCM2 |
| Long gene name: |
CCM2 scaffolding protein |
| Synonyms gene: |
C7orf22 |
| Synonyms gene name: |
chromosome 7 open reading frame 22 cerebral cavernous malformation 2 |
| Synonyms: |
MGC4607 OSM |
| Synonyms name: |
malcavernin osmosensing scaffold for MEKK3 |
| Locus: |
7p13 |
| Discovery year: |
2003-07-14 |
| GenBank acession: |
BC004903 |
| Entrez gene record: |
83605 |
| Pubmed identfication: |
9811928 |
| RefSeq identity: |
NM_031443 |
| Havana BLAST/BLAT: |
OTTHUMG00000129246 |
| Locus Specific Databases: |
LRG_664 |