| known also as: |
ACTR-I, ACVRLK2), ALK-2, Activin Receptor Type I, Activin Receptor-like Kinase 2, NT (Activin Receptor Type 1, SKR1, Serine/Threonine-protein Kinase Receptor R1, TGF-B Superfamily Receptor Type I, TSR-I, Anti-ACVR1 |
| known also as: |
ACTR-I, ACVRLK2), ALK-2, Activin Receptor Type I, Activin Receptor-like Kinase 2, NT (Activin Receptor Type 1, SKR1, Serine/Threonine-protein Kinase Receptor R1, TGF-B Superfamily Receptor Type I, TSR-I, ACVR1 |
| known also as: |
ACTR-I, ACVRLK2), ALK-2, Activin Receptor Type I, Activin Receptor-like Kinase 2, NT (Activin Receptor Type 1, SKR1, Serine/Threonine-protein Kinase Receptor R1, TGF-B Superfamily Receptor Type I, TSR-I, ACVR1 |
| known also as: |
ACVR1 |
| known also as: |
ACTR-I, ACVRLK2), ALK-2, Activin Receptor Type I, Activin Receptor-like Kinase 2, NT (Activin Receptor Type 1, SKR1, Serine/Threonine-protein Kinase Receptor R1, TGF-B Superfamily Receptor Type I, TSR-I, Anti -ACVR1 |
| Other names: |
ACTR-I, ALK-2, Activin receptor type I, Activin receptor type-1, Activin receptor-like kinase 2, OTTHUMP00000162806, OTTHUMP00000204626, OTTHUMP00000240120, SKR1, Serine/threonine-protein kinase receptor R1, TGF-B superfamily receptor type I, TGF-B superfamily receptor type I, activin A receptor, activin A receptor, activin receptor type I, activin receptor type-1, activin receptor-like kinase 2, hydroxyalkyl-protein kinase, serine/threonine-protein kinase receptor R1, type I, type II-like kinase 2, activin receptor type-1 |
| Other gene names: |
ACTRI, ACVR1, ACVR1A, ACVRLK2, ACVRLK2, ALK2, FOP, SKR1, TSRI, ACVR1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Mouse, Human |
| Specificity and cross-reactivity: |
Species Crossreactivity: mouse, Recognizes human ACVR1 |
| Purification method: |
Purified by ammonium sulfate precipitation |
| Form/Appearance: |
0, 09% sodium azide, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquot to avoid repeated freezing and thawing, Aliquots are stable for 12 months, For maximum recovery of product, For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunohistochemistry (IHC), Western Blot (WB), ELISA (EL/EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
ACTR-I, ACVRLK2), ALK-2, Activin Receptor I, Activin Receptor-like Kinase 2, NT (Activin Receptor 1, SKR1, Serine/Threonine-protein Kinase Receptor R1, TGF-B Superfamily Receptor I, TSR-I, ACVR1 |
| Short name: |
ACTR-I, ACVRLK2) Antibody, ALK-2, Activin Receptor I, Activin Receptor-like Kinase 2, NT (Activin Receptor 1, SKR1, Serine/Threonine-protein Kinase Receptor R1, TGF-B Superfamily Receptor I, TSR-I, ACVR1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ACTR-I, ACVRLK2) (Antibody to), Activin Receptor classification I, Activin Receptor-like phosphorylation catalyst 2, NT (Activin Receptor classification 1, SKR1, Serine/Threonine-protein phosphorylation catalyst Receptor R1, TGF-B supergroup Receptor classification I, TSR-I, anaplastic lymphoma receptor tyrosine kinase-2, classification I, activin A receptor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ACTRI and ACVR1A and ACVRLK2 and ALK2 and FOP and SKR1 and TSRI, ACVR1 and IDBG-641620 and ENSBTAG00000011909 and 338068, ACVR1 and IDBG-72930 and ENSG00000115170 and 90, ALK and IDBG-42084 and ENSG00000171094 and 238, ALK and IDBG-636042 and ENSBTAG00000007379 and 536642, Acvr1 and IDBG-172102 and ENSMUSG00000026836 and 11477, Alk and IDBG-197259 and ENSMUSG00000055471 and 11682, CD246 and NBLST3, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046332 and SMAD binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0048179 and activin receptor complex and cellular component this GO :0048185 and activin binding and molecular function this GO :0048641 and regulation of skeletal muscle tissue development and biological process this GO :0050431 and transforming growth factor beta binding and molecular function this GO :0051145 and smooth muscle cell differentiation and biological process this GO :0060037 and pharyngeal system development and biological process this GO :0060389 and pathway-restricted SMAD protein phosphorylation and biological process this GO :0060923 and cardiac muscle cell fate commitment and biological process this GO :0061445 and endocardial cushion cell fate commitment and biological process this GO :0071385 and cellular response to glucocorticoid stimulus and biological process this GO :2000017 and positive regulation of determination of dorsal identity and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process, Plasma membranes, Plasma membranes, activin A receptor, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0001569 and patterning of blood vessels and biological process this GO :0001655 and urogenital system development and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001702 and gastrulation with mouth forming second and biological process this GO :0001707 and mesoderm formation and biological process this GO :0001755 and neural crest cell migration and biological process this GO :0002526 and acute inflammatory response and biological process this GO :0003143 and embryonic heart tube morphogenesis and biological process this GO :0003183 and mitral valve morphogenesis and biological process this GO :0003289 and atrial septum primum morphogenesis and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004675 and transmembrane receptor protein serine/threonine kinase activity and molecular function this GO :0004702 and receptor signaling protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005024 and transforming growth factor beta-activated receptor activity and molecular function this GO :0005025 and transforming growth factor beta receptor activity, this GO :0000187 and activation of MAPK activity and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004704 and NF-kappaB-inducing kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016310 and phosphorylation and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004675 : transmembrane receptor protein serine/threonine kinase activity and also this GO :0004702 : receptor signaling protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005024 : transforming growth factor beta-activated receptor activity and also this GO :0005025 : transforming growth factor beta receptor activity, this GO :0004672 : protein kinase activity and also this GO :0004704 : NF-kappaB-inducing kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004675 : transmembrane receptor protein serine/threonine kinase activity, this GO :0004702 : receptor signaling protein serine/threonine kinase activity, this GO :0004704 : NF-kappaB-inducing kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0005024 : transforming growth factor beta-activated receptor activity, this GO :0005025 : transforming growth factor beta receptor activity, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005524 : ATP binding, this GO :0016361 : activin receptor activity, this GO :0016772 : transferase activity, this GO :0016772 : transferase activity, this GO :0017046 : peptide hormone binding, this GO :0019838 : growth factor binding, this GO :0042803 : protein homodimerization activity, this GO :0046332 : SMAD binding, this GO :0046872 : metal ion binding, this GO :0048185 : activin binding, this GO :0050431 : transforming growth factor beta binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017046 : peptide hormone binding and also this GO :0019838 : growth factor binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046332 : SMAD binding and also this GO :0046872 : metal ion binding and also this GO :0048185 : activin binding and also this GO :0050431 : transforming growth factor beta binding, transferring phosphorus-containing groups and molecular function this GO :0017046 and peptide hormone binding and molecular function this GO :0018107 and peptidyl-threonine phosphorylation and biological process this GO :0019838 and growth factor binding and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030278 and regulation of ossification and biological process this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0032924 and activin receptor signaling pathway and biological process this GO :0032926 and negative regulation of activin receptor signaling pathway and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045177 and apical part of cell and cellular component this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045893 and positive regulation of transcription, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0038061 and NIK/NF-kappaB signaling and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0046777 and protein autophosphorylation and biological process this GO :0048666 and neuron development and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, transforming growth factor beta receptor activity, type I, type I, type I, type I and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016361 : activin receptor activity, type I and also this GO :0016772 : transferase activity, type I and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007178 and transmembrane receptor protein serine/threonine kinase signaling pathway and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007281 and germ cell development and biological process this GO :0007368 and determination of left/right symmetry and biological process this GO :0007369 and gastrulation and biological process this GO :0007498 and mesoderm development and biological process this GO :0007507 and heart development and biological process this GO :0009968 and negative regulation of signal transduction and biological process this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0016020 and membrane and cellular component this GO :0016361 and activin receptor activity, type I and molecular function this GO :0016772 and transferase activity, anaplastic lymphoma receptor tyrosine kinase |
| Identity: |
171 |
| Gene: |
ACVR1 |
More about : ACVR1 |
| Long gene name: |
activin A receptor type 1 |
| Synonyms gene: |
ACVRLK2 |
| Synonyms gene name: |
activin A receptor, type I |
| Synonyms: |
SKR1 ALK2 ACVR1A |
| Locus: |
2q24, 1 |
| Discovery year: |
1994-01-10 |
| Entrez gene record: |
90 |
| Pubmed identfication: |
8397373 |
| RefSeq identity: |
NM_001105 |
| Classification: |
Type 1 receptor serine/threonine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000131967 |