| Also known as: |
DARC |
| Other names: |
Duffy antigen/chemokine receptor, Duffy antigen/chemokine receptor, Duffy blood group, Duffy blood group, Duffy blood group antigen, Fy glycoprotein, Fy glycoprotein, Glycoprotein D, GpFy, Plasmodium vivax receptor, atypical chemokine receptor, atypical chemokine receptor 1, chemokine receptor, glycoprotein D, plasmodium vivax receptor, Duffy antigen/chemokine receptor isoform a |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ACKR1, CCBP1, CD234, DARC, Dfy, FY, FY, GPD, GPD, GpFy, GpFy, WBCQ1, DARC |
| Gene name synonims: |
ACKR1, CCBP1, CD234, DARC, Dfy, FY, FY, GPD, GPD, GpFy, GpFy, WBCQ1, DARC |
| Other gene names: |
ACKR1, CCBP1, CD234, DARC, Dfy, FY, FY, GPD, GPD, GpFy, GpFy, WBCQ1, DARC |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
7H31 |
| Host organism: |
Mouse (Mus musculus) |
| Source organism: |
Human (Homo sapiens) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Recognizes human DARC |
| Purification method: |
Affinity Purified by Protein G affinity chromatography |
| Form/Appearance: |
0, Labeled with APC, 1% sodium azide, Supplied as a liquid in PBS |
| Storage and shipping: |
APC conjugates are sensitive to light, DO NOT FREEZE! Stable at Store the antibody at +4 degrees Celsius, Dilute only prior to immediate use, Freezing APC conjugates will result in a substantial loss of activity, If further dilution(s) are needed, Prior to use, Stable for 12 months, as an undiluted liquid, before opening, briefly centrifuge the original vial after thawing and before lid, they can be done with the appropriate assay buffer, May be stored at Store the antibody at +4 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FC/FACS) |
| Description: |
present in lysates used as reference for ELISA quantification of these molecules and their subunits, Whole adhesion and interacting molecules are |
| Gene target: |
Adhesion Molecule 3, CADM3) (APC), GpFy, DARC (Duffy Fy Glycoprotein |
| Short name: |
CADM3) (APC), Cell Adhesion Molecule 3, Fy Glycoprotein, GpFy, DARC (Duffy Antigen |
| Label: |
APC |
| Alternative name: |
Fy Glycoprotein, GpFy, cellular Adhesion Molecule 3, cellular adhesion molecule 3) (adenomatous polyposis coli), chemokine receptor (Duffy protein, Duffy blood group |
| Alternative to gene target: |
APC and IDBG-37007 and ENSG00000134982 and 324, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT, BT, BTPS2 and DP2 and DP2, C-C chemokine binding, CADM3 and IDBG-103868 and ENSG00000162706 and 57863, CADM3 and IDBG-630783 and ENSBTAG00000003217 and 531178, CCBP1 and CD234 and DARC and Dfy and FY and GPD and GpFy and WBCQ1, Cadm3 and IDBG-205840 and ENSMUSG00000005338 and 94332, Cell surfaces, DARC and IDBG-246055 and ENSG00000213088 and 2532, Darc and IDBG-205828 and ENSMUSG00000037872 and 13349, Duffy blood group, Plasma membranes, cell adhesion molecule 3, chemokine receptor, microtubule plus-end binding, nuclei, protein homodimerization activity, this GO :0000281 and mitotic cytokinesis and biological process this GO :0000776 and kinetochore and cellular component this GO :0001822 and kidney development and biological process this GO :0001942 and hair follicle development and biological process this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005881 and cytoplasmic microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0005923 and tight junction and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007026 and negative regulation of microtubule depolymerization and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007091 and metaphase/anaphase transition of mitotic cell cycle and biological process this GO :0007094 and mitotic spindle assembly checkpoint and biological process this GO :0007155 and cell adhesion and biological process this GO :0007389 and pattern specification process and biological process this GO :0007409 and axonogenesis and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0008017 and microtubule binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009798 and axis specification and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0009953 and dorsal/ventral pattern formation and biological process this GO :0009954 and proximal/distal pattern formation and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016328 and lateral plasma membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0019827 and stem cell maintenance and biological process this GO :0019887 and protein kinase regulator activity and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030027 and lamellipodium and cellular component this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030424 and axon and cellular component this GO :0030426 and growth cone and cellular component this GO :0030856 and regulation of epithelial cell differentiation and biological process this GO :0030858 and positive regulation of epithelial cell differentiation and biological process this GO :0030877 and beta-catenin destruction complex and cellular component this GO :0031116 and positive regulation of microtubule polymerization and biological process this GO :0031122 and cytoplasmic microtubule organization and biological process this GO :0031253 and cell projection membrane and cellular component this GO :0031274 and positive regulation of pseudopodium assembly and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0032886 and regulation of microtubule-based process and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0035371 and microtubule plus-end and cellular component this GO :0042483 and negative regulation of odontogenesis and biological process this GO :0042995 and cell projection and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0043588 and skin development and biological process this GO :0044295 and axonal growth cone and cellular component this GO :0044336 and canonical Wnt signaling pathway involved in negative regulation of apoptotic process and biological process this GO :0044337 and canonical Wnt signaling pathway involved in positive regulation of apoptotic process and biological process this GO :0045295 and gamma-catenin binding and molecular function this GO :0045595 and regulation of cell differentiation and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045667 and regulation of osteoblast differentiation and biological process this GO :0045670 and regulation of osteoclast differentiation and biological process this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0045736 and negative regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0046716 and muscle cell cellular homeostasis and biological process this GO :0048538 and thymus development and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0051010 and microtubule plus-end binding and molecular function this GO :0051171 and regulation of nitrogen compound metabolic process and biological process this GO :0051276 and chromosome organization and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0051781 and positive regulation of cell division and biological process this GO :0051988 and regulation of attachment of spindle microtubules to kinetochore and biological process this GO :0060041 and retina development in camera-type eye and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060770 and negative regulation of epithelial cell proliferation involved in prostate gland development and biological process this GO :0070830 and tight junction assembly and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process, this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005769 and early endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006952 and defense response and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0019956 and chemokine binding and molecular function this GO :0019957 and C-C chemokine binding and molecular function this GO :0032642 and regulation of chemokine production and biological process this GO :0055037 and recycling endosome and cellular component this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0019956 : chemokine binding and also this GO :0019957 : C-C chemokine binding, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004930 : G-protein coupled receptor activity, this GO :0005488 : binding, this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0008013 : beta-catenin binding and also this GO :0008017 : microtubule binding and also this GO :0019887 : protein kinase regulator activity and also this GO :0019901 : protein kinase binding and also this GO :0045295 : gamma-catenin binding and also this GO :0051010 : microtubule plus-end binding, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0007156 and homophilic cell adhesion and biological process this GO :0007157 and heterophilic cell-cell adhesion and biological process this GO :0008104 and protein localization and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0034329 and cell junction assembly and biological process this GO :0034332 and adherens junction organization and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045216 and cell-cell junction organization and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0042803 : protein homodimerization activity, this GO :0008013 : beta-catenin binding, this GO :0008017 : microtubule binding, this GO :0019887 : protein kinase regulator activity, this GO :0019901 : protein kinase binding, this GO :0019956 : chemokine binding, this GO :0019957 : C-C chemokine binding, this GO :0042803 : protein homodimerization activity, this GO :0045295 : gamma-catenin binding, this GO :0051010 : microtubule plus-end binding, 25770 and IDBG-644937 and ENSBTAG00000018852 and 533233, 27077 and IDBG-630777 and ENSBTAG00000003220 and 528076, 5 and DP3 and GS and PPP1R46, adenomatous polyposis coli |
| Identity: |
17601 |
| Gene: |
CADM3 |
More about : CADM3 |
| Long gene name: |
cell adhesion molecule 3 |
| Synonyms gene: |
IGSF4B |
| Synonyms gene name: |
immunoglobulin superfamily, member 4B |
| Synonyms: |
BIgR FLJ10698 TSLL1 NECL1 SynCAM3 Necl-1 |
| Synonyms name: |
nectin-like 1 |
| Locus: |
1q23, 2 |
| Discovery year: |
2004-02-24 |
| GenBank acession: |
AY046418 |
| Entrez gene record: |
57863 |
| Pubmed identfication: |
11536053 |
| RefSeq identity: |
NM_021189 |
| Classification: |
C2-set domain containing Immunoglobulin like domain containing V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000037177 |