| known also as: |
Duo, FLJ16443, HAPIP, Huntingtin-associated Protein-interacting Protein (duo), KALRN, Kalirin, Kalirin (isoform 2), Serine/threonine Kinase with Dbl and Pleckstrin Homology Domains, TRAD), Anti-RhoGEF Kinase (DUET |
| known also as: |
Duo, FLJ16443, HAPIP, Huntingtin-associated Protein-interacting Protein (duo), KALRN, Kalirin, Kalirin (isoform 2), Serine/threonine Kinase with Dbl and Pleckstrin Homology Domains, TRAD), RhoGEF Kinase (DUET |
| known also as: |
Duo, FLJ16443, HAPIP, Huntingtin-associated Protein-interacting Protein (duo), KALRN, Kalirin, Kalirin (isoform 2), Serine/threonine Kinase with Dbl and Pleckstrin Homology Domains, TRAD), RhoGEF Kinase (DUET |
| known also as: |
RhoGEF Kinase |
| known also as: |
Duo, FLJ16443, HAPIP, Huntingtin-associated Protein-interacting Protein (duo), KALRN, Kalirin, Kalirin (isoform 2), Serine/threonine Kinase with Dbl and Pleckstrin Homology Domains, TRAD), Anti -RhoGEF Kinase (DUET |
| Other names: |
N/A, N/A, Rho guanine nucleotide exchange factor (GEF) 11, rho guanine nucleotide exchange factor 11, rho guanine nucleotide exchange factor 11 |
| Other gene names: |
B930073M02, E130307F09, N/A, N/A, PDZ-RhoGEF, Prg, RhoGEF, mKIAA0380, Arhgef11 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Species sequence homology: mouse, bovine, equine, rat, 1 of human RhoGEF Kinase, 2 and NP_003938, Recognizes isoforms NP_001019831 |
| Purification method: |
Affinity Purified by affinity chromatography |
| Form/Appearance: |
0, 0, pH 7, 02% sodium azide, 2, 5% BSA, Supplied as a liquid in Tris |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
ELISA (EL/EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
Duo, FLJ16443, Huntingtin-associated Protein-interacting Protein (duo) HAPIP, KALRN, Kalirin (isoform 2) Kalirin, Serine/threonine Kinase with Dbl Pleckstrin Homology Domains, TRAD), RhoGEF Kinase (DUET |
| Short name: |
Duo, FLJ16443, Huntingtin-associated Protein-interacting Protein (duo) HAPIP, KALRN, Kalirin (isoform 2) Kalirin, Serine/threonine Kinase with Dbl Pleckstrin Homology Domains, TRAD), RhoGEF Kinase (DUET |
| Alternative name: |
Duo, FLJ16443, HAPIP, Huntingtin-associated Protein-interacting Protein (duo), Kalirin, Kalirin (isoform 2), RhoGEF kinase, Serine/threonine phosphorylation catalyst including Dbl and Pleckstrin Homology Domains, TRAD), kalirin, RhoGEF phosphorylation catalyst (DUET |
| Alternative to gene target: |
ARHGEF24 and CHD5 and CHDS5 and DUET and DUO and HAPIP and TRAD, Cytoplasm, KALRN and IDBG-53661 and ENSG00000160145 and 8997, KALRN and IDBG-633466 and ENSBTAG00000002640 and 540675, Kalrn and IDBG-155984 and ENSMUSG00000061751 and 545156, RhoGEF kinase, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007399 and nervous system development and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016192 and vesicle-mediated transport and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005085 : guanyl-nucleotide exchange factor activity and also this GO :0005089 : Rho guanyl-nucleotide exchange factor activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005085 : guanyl-nucleotide exchange factor activity, this GO :0005089 : Rho guanyl-nucleotide exchange factor activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0046872 : metal ion binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0046872 : metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0097190 and apoptotic signaling pathway and biological process, kalirin |
| Identity: |
4814 |
| Gene: |
KALRN |
More about : KALRN |
| Long gene name: |
RhoGEF kinase , kalirin |
| Synonyms gene: |
HAPIP |
| Synonyms gene name: |
huntingtin-associated protein interacting protein (duo) |
| Synonyms: |
duo Hs, 8004 TRAD DUET Kalirin ARHGEF24 |
| Synonyms name: |
serine/threonine kinase with Dbl and pleckstrin homology domains |
| Locus: |
3q21, 1-q21, 2 |
| Discovery year: |
1999-01-13 |
| GenBank acession: |
U94190 |
| Entrez gene record: |
8997 |
| Pubmed identfication: |
9285789 10023074 |
| RefSeq identity: |
NM_003947 |
| Classification: |
Rho guanine nucleotide exchange factors I-set domain containing Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000125545 |