| known also as: |
CD288, CD288 Antigen, MGC119599, MGC119600), TLR 8, Toll-like Receptor 8, Anti-TLR8 (Toll Like Receptor 8 |
| known also as: |
CD288, CD288 Antigen, MGC119599, MGC119600), TLR 8, Toll-like Receptor 8, TLR8 (Toll Like Receptor 8 |
| known also as: |
CD288, CD288 Antigen, MGC119599, MGC119600), TLR 8, Toll-like Receptor 8, TLR8 (Toll Like Receptor 8 |
| known also as: |
TLR8 |
| known also as: |
CD288, CD288 Antigen, MGC119599, MGC119600), TLR 8, Toll-like Receptor 8, Anti -TLR8 (Toll Like Receptor 8 |
| Other names: |
N/A, TLR8 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Mouse, Human |
| Specificity and cross-reactivity: |
Species Crossreactivity: mouse, Recognizes human TLR8 |
| Purification method: |
Highly Purified by Ion Exchange chromatography |
| Form/Appearance: |
0, 02% sodium azide, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, add sterile 40-50% glycerol, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
CD288, CD288 MGC119599, MGC119600), TLR 8, Toll-like Receptor 8, TLR8 (Toll Like Receptor 8 |
| Short name: |
CD288, CD288 Antigen, MGC119599, MGC119600), TLR 8, Toll-like Receptor 8, TLR8 (Toll Like Receptor 8 |
| Alternative name: |
CD288, CD288 protein, MGC119599, MGC119600), Toll-like Receptor 8, Toll-like receptor 8, toll-like receptor 8 (Toll Like Receptor 8 |
| Alternative to gene target: |
Plasma membranes, TLR8 and IDBG-44288 and ENSG00000101916 and 51311, Tlr8 and IDBG-185523 and ENSMUSG00000040522 and 170744, drug binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001774 and microglial cell activation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0003677 and DNA binding and molecular function this GO :0003723 and RNA binding and molecular function this GO :0003725 and double-stranded RNA binding and molecular function this GO :0003727 and single-stranded RNA binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0008144 and drug binding and molecular function this GO :0009615 and response to virus and biological process this GO :0010008 and endosome membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016064 and immunoglobulin mediated immune response and biological process this GO :0034158 and toll-like receptor 8 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0036020 and endolysosome membrane and cellular component this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045089 and positive regulation of innate immune response and biological process this GO :0045356 and positive regulation of interferon-alpha biosynthetic process and biological process this GO :0045359 and positive regulation of interferon-beta biosynthetic process and biological process this GO :0045416 and positive regulation of interleukin-8 biosynthetic process and biological process this GO :0050707 and regulation of cytokine secretion and biological process this GO :0051607 and defense response to virus and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003723 : RNA binding and also this GO :0003725 : double-stranded RNA binding and also this GO :0003727 : single-stranded RNA binding and also this GO :0004872 : receptor activity and also this GO :0005515 : protein binding and also this GO :0008144 : drug binding, this GO :0003723 : RNA binding, this GO :0003725 : double-stranded RNA binding, this GO :0003727 : single-stranded RNA binding, this GO :0004872 : receptor activity, this GO :0005515 : protein binding, this GO :0008144 : drug binding, toll-like receptor 8 |
| Identity: |
15632 |
| Gene: |
TLR8 |
More about : TLR8 |
| Long gene name: |
toll like receptor 8 |
| Synonyms gene name: |
toll-like receptor 8 |
| Synonyms: |
CD288 |
| Locus: |
Xp22, 2 |
| Discovery year: |
2001-04-27 |
| GenBank acession: |
AF246971 |
| Entrez gene record: |
51311 |
| Pubmed identfication: |
11022119 |
| RefSeq identity: |
NM_016610 |
| Classification: |
CD molecules Toll like receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000021145 |
| Locus Specific Databases: |
Mental Retardation database |