| known also as: |
DFNA14, DFNA38, DFNA6, DIDMOAD), WFRS, WFS, Wolfram Syndrome, Wolframin, Anti-WFS1 (Wolfram Syndrome 1 (Wolframin) |
| known also as: |
DFNA14, DFNA38, DFNA6, DIDMOAD), WFRS, WFS, Wolfram Syndrome, Wolframin, WFS1 (Wolfram Syndrome 1 (Wolframin) |
| known also as: |
DFNA14, DFNA38, DFNA6, DIDMOAD), WFRS, WFS, Wolfram Syndrome, Wolframin, WFS1 (Wolfram Syndrome 1 (Wolframin) |
| known also as: |
WFS1 |
| known also as: |
DFNA14, DFNA38, DFNA6, DIDMOAD), WFRS, WFS, Wolfram Syndrome, Wolframin, Anti -WFS1 (Wolfram Syndrome 1 (Wolframin) |
| Other names: |
N/A, Wolfram syndrome 1 (wolframin), Wolframin, wolframin, wolframin |
| Other gene names: |
N/A, WFRS, WFS, WFS1, WFSL, WFS1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Mouse, Rat, Human |
| Specificity and cross-reactivity: |
Species crossreactivity: mouse and rat, Recognizes human WFS1 protein at ~100kD |
| Purification method: |
Serum |
| Form/Appearance: |
Supplied as a liquid |
| Storage and shipping: |
Aliquot to avoid repeated freezing and thawing, Aliquots are stable for at least 12 months, For maximum recovery of product, For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
DFNA14, DFNA38, DFNA6, DIDMOAD), WFRS, WFS, Wolframin, WFS1 (Wolfram Syndrome 1 (Wolframin) Wolfram Syndrome |
| Short name: |
DFNA14, DFNA38, DFNA6, DIDMOAD) Antibody, WFRS, WFS, Wolframin, WFS1 (Wolfram Syndrome 1 (Wolframin) Wolfram Syndrome |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DFNA14, DFNA38, DFNA6, DIDMOAD) (Antibody to), WFRS, WFS, Wolfram Syndrome, Wolframin, Wolfram syndrome 1 (wolframin) (Wolfram Syndrome 1 (Wolframin) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ATPase binding, CTRCT41 and WFRS and WFS and WFSL, Cytoplasm, WFS1 and IDBG-643358 and ENSBTAG00000046671 and 100298456, WFS1 and IDBG-8903 and ENSG00000109501 and 7466, Wfs1 and IDBG-158640 and ENSMUSG00000039474 and 22393, this GO :0001822 and kidney development and biological process this GO :0003091 and renal water homeostasis and biological process this GO :0005215 and transporter activity and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006983 and ER overload response and biological process this GO :0006987 and activation of signaling protein activity involved in unfolded protein response and biological process this GO :0007601 and visual perception and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0022417 and protein maturation by protein folding and biological process this GO :0030176 and integral component of endoplasmic reticulum membrane and cellular component this GO :0030425 and dendrite and cellular component this GO :0030433 and ER-associated ubiquitin-dependent protein catabolic process and biological process this GO :0030968 and endoplasmic reticulum unfolded protein response and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032469 and endoplasmic reticulum calcium ion homeostasis and biological process this GO :0033613 and activating transcription factor binding and molecular function this GO :0034976 and response to endoplasmic reticulum stress and biological process this GO :0042048 and olfactory behavior and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0043069 and negative regulation of programmed cell death and biological process this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045862 and positive regulation of proteolysis and biological process this GO :0045927 and positive regulation of growth and biological process this GO :0048306 and calcium-dependent protein binding and molecular function this GO :0050821 and protein stabilization and biological process this GO :0050877 and neurological system process and biological process this GO :0051117 and ATPase binding and molecular function this GO :0051247 and positive regulation of protein metabolic process and biological process this GO :0051928 and positive regulation of calcium ion transport and biological process this GO :0055074 and calcium ion homeostasis and biological process this GO :0070845 and polyubiquitinated misfolded protein transport and biological process this GO :1902236 and negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and biological process this GO :2000675 and negative regulation of type B pancreatic cell apoptotic process and biological process, this GO :0005215 : transporter activity, this GO :0005215 : transporter activity and also this GO :0005516 : calmodulin binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0033613 : activating transcription factor binding and also this GO :0048306 : calcium-dependent protein binding and also this GO :0051117 : ATPase binding, this GO :0005516 : calmodulin binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0033613 : activating transcription factor binding, this GO :0048306 : calcium-dependent protein binding, this GO :0051117 : ATPase binding, Wolfram syndrome 1 (wolframin) |
| Identity: |
12762 |
| Gene: |
WFS1 |
More about : WFS1 |
| Long gene name: |
wolframin ER transmembrane glycoprotein |
| Synonyms gene: |
DFNA6 DFNA14 DFNA38 |
| Synonyms gene name: |
Wolfram syndrome 1 (wolframin) |
| Synonyms: |
DIDMOAD WFS |
| Locus: |
4p16, 1 |
| Discovery year: |
1995-01-30 |
| GenBank acession: |
AF084481 |
| Entrez gene record: |
7466 |
| Pubmed identfication: |
7987399 9771706 |
| Havana BLAST/BLAT: |
OTTHUMG00000090431 |
| Locus Specific Databases: |
Hereditary Hearing Loss Homepage |