| known also as: |
BANF, CN, NF2), Neurofibromatosis-2, Neurofibromin 2, SCH, Schwannomerlin, phosphorylated (Ser518) (Schwannomin, Anti-Merlin |
| known also as: |
BANF, CN, NF2), Neurofibromatosis-2, Neurofibromin 2, SCH, Schwannomerlin, phosphorylated (Ser518) (Schwannomin, Merlin |
| known also as: |
BANF, CN, NF2), Neurofibromatosis-2, Neurofibromin 2, SCH, Schwannomerlin, phosphorylated (Ser518) (Schwannomin, Merlin |
| known also as: |
Merlin |
| known also as: |
BANF, CN, NF2), Neurofibromatosis-2, Neurofibromin 2, SCH, Schwannomerlin, phosphorylated (Ser518) (Schwannomin, Anti -Merlin |
| Other names: |
Merlin, Moesin-ezrin-radixin-like protein, Neurofibromin-2, Schwannomerlin, Schwannomin, merlin, moesin-ezrin-radixin like, moesin-ezrin-radixin-like protein, moesin-ezrin-radizin-like protein, neurofibromin 2 (bilateral acoustic neuroma), neurofibromin 2 (merlin), neurofibromin-2, schwannomerlin, schwannomin, merlin isoform 7 |
| Other gene names: |
ACN, BANF, NF2, SCH, SCH, NF2 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Mouse, Human |
| Specificity and cross-reactivity: |
Reactivity with non-phosphorylated human NF2 (Merlin) is minimal by ELISA, Species Crossreactivity: mouse, Recognizes phosphorylated pS518 of human NF2 |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Form/Appearance: |
0, 0, pH 7, 01% sodium azide, 02M potassium phosphate, 15M sodium chloride, 2, Supplied as a liquid in 0 |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB), ELISA (EL/EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
BANF, CN, NF2), Neurofibromatosis-2, Neurofibromin 2, SCH, Schwannomerlin, phosphorylated (Ser518) (Schwannomin, Merlin |
| Short name: |
BANF, CN, NF2) Antibody, Neurofibromatosis-2, Neurofibromin 2, SCH, Schwannomerlin, phosphorylated (Ser518) (Schwannomin, Merlin |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
BANF, CN, Neurofibromatosis-2, Neurofibromin 2, SCH, Schwannomerlin, neurofibromin 2 (merlin)) (Antibody to), phosphorylated (Ser518) (Schwannomin, Merlin |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ACN and BANF and SCH, NF2 and IDBG-3678 and ENSG00000186575 and 4771, NF2 and IDBG-636202 and ENSBTAG00000013153 and 540479, Nf2 and IDBG-142996 and ENSMUSG00000009073 and 18016, cytoskeletal protein binding, nuclei, this GO :0001707 and mesoderm formation and biological process this GO :0001726 and ruffle and cellular component this GO :0001953 and negative regulation of cell-matrix adhesion and biological process this GO :0003779 and actin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005769 and early endosome and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005912 and adherens junction and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0007398 and ectoderm development and biological process this GO :0007420 and brain development and biological process this GO :0008092 and cytoskeletal protein binding and molecular function this GO :0008156 and negative regulation of DNA replication and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0014010 and Schwann cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0019898 and extrinsic component of membrane and cellular component this GO :0021766 and hippocampus development and biological process this GO :0022408 and negative regulation of cell-cell adhesion and biological process this GO :0030027 and lamellipodium and cellular component this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030175 and filopodium and cellular component this GO :0030336 and negative regulation of cell migration and biological process this GO :0030864 and cortical actin cytoskeleton and cellular component this GO :0031527 and filopodium membrane and cellular component this GO :0031647 and regulation of protein stability and biological process this GO :0032154 and cleavage furrow and cellular component this GO :0032587 and ruffle membrane and cellular component this GO :0035330 and regulation of hippo signaling and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042518 and negative regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0042524 and negative regulation of tyrosine phosphorylation of Stat5 protein and biological process this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0045177 and apical part of cell and cellular component this GO :0045216 and cell-cell junction organization and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0046426 and negative regulation of JAK-STAT cascade and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051496 and positive regulation of stress fiber assembly and biological process this GO :0070306 and lens fiber cell differentiation and biological process this GO :1900180 and regulation of protein localization to nucleus and biological process this GO :2000177 and regulation of neural precursor cell proliferation and biological process, this GO :0003779 : actin binding, this GO :0003779 : actin binding and also this GO :0005515 : protein binding and also this GO :0008092 : cytoskeletal protein binding, this GO :0005515 : protein binding, this GO :0008092 : cytoskeletal protein binding, neurofibromin 2 (merlin) |
| Identity: |
7773 |
| Gene: |
NF2 |
More about : NF2 |
| Long gene name: |
neurofibromin 2 |
| Synonyms gene name: |
neurofibromin 2 (bilateral acoustic neuroma) neurofibromin 2 (merlin) |
| Synonyms: |
merlin ACN SCH BANF |
| Synonyms name: |
moesin-ezrin-radixin like schwannomin |
| Locus: |
22q12, 2 |
| Discovery year: |
1992-01-01 |
| GenBank acession: |
L11353 |
| Entrez gene record: |
4771 |
| Pubmed identfication: |
10591208 |
| RefSeq identity: |
NM_000268 |
| Classification: |
A-kinase anchoring proteins FERM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000030727 |
| Locus Specific Databases: |
Neurofibromatosis 2 (NF2) mutation database LRG_511 |