| known also as: |
DKFZP686M05248, EC 1, MGC102856, MGC42116, P53R2, RRM2B), TP53 Inducible (RRM2B, 1, 4, 17, Anti-Ribonucleotide Reductase M2B |
| known also as: |
DKFZP686M05248, EC 1, MGC102856, MGC42116, P53R2, RRM2B), TP53 Inducible (RRM2B, 1, 4, 17, Ribonucleotide Reductase M2B |
| known also as: |
DKFZP686M05248, EC 1, MGC102856, MGC42116, P53R2, RRM2B), TP53 Inducible (RRM2B, 1, 4, 17, Ribonucleotide Reductase M2B |
| known also as: |
TP53 Inducible, Ribonucleotide Reductase M2B |
| known also as: |
DKFZP686M05248, EC 1, MGC102856, MGC42116, P53R2, RRM2B), TP53 Inducible (RRM2B, 1, 4, 17, Anti -Ribonucleotide Reductase M2B |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Mouse, Rat, Species Crossreactivity: Human, Recognizes Human Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B/P53R2) |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Form/Appearance: |
0, 02% sodium azide, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunohistochemistry (IHC), Western Blot (WB), ELISA (EL/EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
DKFZP686M05248, EC 1, MGC102856, MGC42116, P53R2, RRM2B), TP53 (RRM2B, 1, 4, 17, Ribonucleotide Reductase M2B |
| Short name: |
DKFZP686M05248, EC 1, MGC102856, MGC42116, P53R2, RRM2B) Antibody, TP53 (RRM2B, 1, 4, 17, Ribonucleotide Reductase M2B |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DKFZP686M05248, EC 1, MGC102856, MGC42116, P53R2, ribonucleotide reductase M2 B (tumor protein p53 inducible)) (Antibody to), tumor protein p53 Inducible (ribonucleotide reductase M2 B (tumor protein p53 inducible), 1, 4, 17, Ribonucleotide Reductase M2B |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BCC7 and LFS1 and P53 and TRP53, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006461 and protein complex assembly and biological process this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006977 and DNA damage response, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046677 and response to antibiotic and biological process this GO :0046872 and metal ion binding and molecular function this GO :0046902 and regulation of mitochondrial membrane permeability and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0047485 and protein N-terminus binding and molecular function this GO :0048147 and negative regulation of fibroblast proliferation and biological process this GO :0048568 and embryonic organ development and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051087 and chaperone binding and molecular function this GO :0051097 and negative regulation of helicase activity and biological process this GO :0051262 and protein tetramerization and biological process this GO :0051276 and chromosome organization and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0051721 and protein phosphatase 2A binding and molecular function this GO :0051726 and regulation of cell cycle and biological process this GO :0070243 and regulation of thymocyte apoptotic process and biological process this GO :0070245 and positive regulation of thymocyte apoptotic process and biological process this GO :0070266 and necroptotic process and biological process this GO :0071158 and positive regulation of cell cycle arrest and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0071479 and cellular response to ionizing radiation and biological process this GO :0071850 and mitotic cell cycle arrest and biological process this GO :0072332 and intrinsic apoptotic signaling pathway by p53 class mediator and biological process this GO :0090200 and positive regulation of release of cytochrome c from mitochondria and biological process this GO :0090343 and positive regulation of cell aging and biological process this GO :0090399 and replicative senescence and biological process this GO :0090403 and oxidative stress-induced premature senescence and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :0097252 and oli this GO dendrocyte apoptotic process and biological process this GO :0097371 and MDM2/MDM4 family protein binding and molecular function this GO :1900740 and positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway and biological process this GO :1901525 and negative regulation of macromitophagy and biological process this GO :1902108 and regulation of mitochondrial membrane permeability involved in apoptotic process and biological process this GO :2000378 and negative regulation of reactive oxygen species metabolic process and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process this GO :2001244 and positive regulation of intrinsic apoptotic signaling pathway and biological process, MDM2/MDM4 family protein binding, RRM2B and IDBG-31119 and ENSG00000048392 and 50484, RRM2B and IDBG-645071 and ENSBTAG00000021208 and 528960, Rrm2b and IDBG-135832 and ENSMUSG00000022292 and 382985, TP53 and IDBG-26364 and ENSG00000141510 and 7157, TP53 and IDBG-635147 and ENSBTAG00000001069 and 281542, Trp53 and IDBG-191036 and ENSMUSG00000059552 and 22059, nuclei, nuclei, ribonucleoside-diphosphate reductase activity, ribonucleotide reductase M2 B (TP53 inducible), signal transduction by p53 class mediator and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030971 and receptor tyrosine kinase binding and molecular function this GO :0031065 and positive regulation of histone deacetylation and biological process this GO :0031497 and chromatin assembly and biological process this GO :0031571 and mitotic G1 DNA damage checkpoint and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032461 and positive regulation of protein oli this GO merization and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0034103 and regulation of tissue remodeling and biological process this GO :0034613 and cellular protein localization and biological process this GO :0034644 and cellular response to UV and biological process this GO :0035033 and histone deacetylase regulator activity and molecular function this GO :0035035 and histone acetyltransferase binding and molecular function this GO :0035264 and multicellular organism growth and biological process this GO :0035690 and cellular response to drug and biological process this GO :0035794 and positive regulation of mitochondrial membrane permeability and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042149 and cellular response to glucose starvation and biological process this GO :0042493 and response to drug and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043523 and regulation of neuron apoptotic process and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045892 and negative regulation of transcription, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0006978 and DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0006983 and ER overload response and biological process this GO :0007049 and cell cycle and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007369 and gastrulation and biological process this GO :0007406 and negative regulation of neuroblast proliferation and biological process this GO :0007417 and central nervous system development and biological process this GO :0007569 and cell aging and biological process this GO :0007596 and blood coagulation and biological process this GO :0008104 and protein localization and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008156 and negative regulation of DNA replication and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008340 and determination of adult lifespan and biological process this GO :0009303 and rRNA transcription and biological process this GO :0009411 and response to UV and biological process this GO :0009651 and response to salt stress and biological process this GO :0009792 and embryo development ending in birth or egg hatching and biological process this GO :0010165 and response to X-ray and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0010666 and positive regulation of cardiac muscle cell apoptotic process and biological process this GO :0016032 and viral process and biological process this GO :0016363 and nuclear matrix and cellular component this GO :0016604 and nuclear body and cellular component this GO :0016605 and PML body and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0021549 and cerebellum development and biological process this GO :0030154 and cell differentiation and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0030330 and DNA damage response, thioredoxin disulfide as acceptor, thioredoxin disulfide as acceptor and also this GO :0046872 : metal ion binding, thioredoxin disulfide as acceptor and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006264 and mitochondrial DNA replication and biological process this GO :0006281 and DNA repair and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0009186 and deoxyribonucleoside diphosphate metabolic process and biological process this GO :0009200 and deoxyribonucleoside triphosphate metabolic process and biological process this GO :0009263 and deoxyribonucleotide biosynthetic process and biological process this GO :0015949 and nucleobase-containing small molecule interconversion and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0046872 and metal ion binding and molecular function this GO :0055086 and nucleobase-containing small molecule metabolic process and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :1902254 and negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator and biological process, this GO :0000060 and protein import into nucleus, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001085 : RNA polymerase II transcription factor binding and also this GO :0001228 : RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0002020 : protease binding and also this GO :0002039 : p53 binding and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003684 : damaged DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005507 : copper ion binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008134 : transcription factor binding and also this GO :0008270 : zinc ion binding and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0019903 : protein phosphatase binding and also this GO :0030971 : receptor tyrosine kinase binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0035033 : histone deacetylase regulator activity and also this GO :0035035 : histone acetyltransferase binding and also this GO :0042802 : identical protein binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046872 : metal ion binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0047485 : protein N-terminus binding and also this GO :0051087 : chaperone binding and also this GO :0051721 : protein phosphatase 2A binding and also this GO :0097371 : MDM2/MDM4 family protein binding, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001085 : RNA polymerase II transcription factor binding, this GO :0001228 : RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001822 and kidney development and biological process this GO :0003014 and renal system process and biological process this GO :0004748 and ribonucleoside-diphosphate reductase activity, this GO :0002020 : protease binding, this GO :0002039 : p53 binding, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003684 : damaged DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0004748 : ribonucleoside-diphosphate reductase activity, this GO :0004748 : ribonucleoside-diphosphate reductase activity, this GO :0005507 : copper ion binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008134 : transcription factor binding, this GO :0008270 : zinc ion binding, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0019903 : protein phosphatase binding, this GO :0030971 : receptor tyrosine kinase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0035033 : histone deacetylase regulator activity, this GO :0035035 : histone acetyltransferase binding, this GO :0042802 : identical protein binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046872 : metal ion binding, this GO :0046872 : metal ion binding, this GO :0046982 : protein heterodimerization activity, this GO :0047485 : protein N-terminus binding, this GO :0051087 : chaperone binding, this GO :0051721 : protein phosphatase 2A binding, this GO :0097371 : MDM2/MDM4 family protein binding, translocation and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000733 and DNA strand renaturation and biological process this GO :0000785 and chromatin and cellular component this GO :0000790 and nuclear chromatin and cellular component this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001085 and RNA polymerase II transcription factor binding and molecular function this GO :0001228 and RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001701 and in utero embryonic development and biological process this GO :0001756 and somitogenesis and biological process this GO :0001836 and release of cytochrome c from mitochondria and biological process this GO :0002020 and protease binding and molecular function this GO :0002039 and p53 binding and molecular function this GO :0002309 and T cell proliferation involved in immune response and biological process this GO :0002326 and B cell lineage commitment and biological process this GO :0002360 and T cell lineage commitment and biological process this GO :0002931 and response to ischemia and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005507 and copper ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005657 and replication fork and cellular component this GO :0005669 and transcription factor TFIID complex and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005829 and cytosol and cellular component this GO :0006284 and base-excision repair and biological process this GO :0006289 and nucleotide-excision repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006351 and transcription, tumor protein p53 |
| Identity: |
17296 |
| Gene: |
RRM2B |
More about : RRM2B |
| Long gene name: |
ribonucleotide reductase regulatory TP53 inducible subunit M2B |
| Synonyms gene name: |
ribonucleotide reductase M2 B (TP53 inducible) |
| Synonyms: |
p53R2 |
| Locus: |
8q22, 3 |
| Discovery year: |
2002-01-14 |
| GenBank acession: |
AB036532 |
| Entrez gene record: |
50484 |
| Pubmed identfication: |
10716435 10980602 17486094 |
| Havana BLAST/BLAT: |
OTTHUMG00000164776 |
| Locus Specific Databases: |
LRG_788 |