| Also known as: |
PLGF |
| Other names: |
N/A, Placenta growth factor, placenta growth factor, placental growth factor, placental growth factor, vascular endothelial growth factor-related protein, placenta growth factor isoform 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
PGF |
| Other gene names: |
D12S1900, PGF, PGFL, PGFL, PLGF, PLGF, PlGF, PlGF-2, SHGC-10760, PGF |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, IgG1 |
| Clone: |
PLGF94 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Evidence has suggested VEGF to be an obligatory component in PlGF signaling, Flt-1, Indeed, Like VEGF, PlGF homodimers are effectual only at extremely high concentrations, Several growth factors with angiogenic activity have been described, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, These include fibroblast growth factor (FGF), This particular antibody might cross react with speacies outside of the listed ones, VEGF and PlGF share a common receptor, While VEGF homodimers and VEGF/PlGF heterodimers function as potent mediators of mitogenic and chemotactic responses in endothelial cells, and may also activate Flk-1/KDR, many of the physiological effects attributed to VEGF may actually be a result of VEGF/PlGF, platelet derived growth factor (PDGF), several PlGF vari- ants have been shown to arise from alternative mRNA splicings, vascular endothelial growth factor (VEGF) and placenta growth factor (PlGF), The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Functional Studies, ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
PLGF |
| Short name: |
PLGF Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PLGF (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8893 |
| Gene: |
PGF |
More about : PGF |
| Long gene name: |
placental growth factor |
| Synonyms gene: |
PGFL |
| Synonyms gene name: |
placental growth factor-like placental growth factor, vascular endothelial growth factor-related protein |
| Synonyms: |
PLGF PlGF-2 PlGF SHGC-10760 D12S1900 PIGF |
| Synonyms name: |
placenta growth factor |
| Locus: |
14q24, 3 |
| Discovery year: |
1994-01-14 |
| GenBank acession: |
S72960 |
| Entrez gene record: |
5228 |
| Pubmed identfication: |
7681160 |
| RefSeq identity: |
NM_002632 |
| Classification: |
VEGF family |
| Havana BLAST/BLAT: |
OTTHUMG00000171496 |