| known also as: |
VISA), Anti-Mitochondrial Antiviral Signaling Protein (MAVS |
| known also as: |
VISA), Mitochondrial Antiviral Signaling Protein (MAVS |
| known also as: |
VISA), Mitochondrial Antiviral Signaling Protein (MAVS |
| known also as: |
Mitochondrial Antiviral Signaling Protein |
| known also as: |
VISA), Anti -Mitochondrial Antiviral Signaling Protein (MAVS |
| Other names: |
CARD adapter inducing interferon beta, CARD adapter inducing interferon beta, CARD adaptor inducing IFN-beta, Cardif, IFN-B promoter stimulator 1, IPS-1, Interferon beta promoter stimulator protein 1, Mitochondrial antiviral-signaling protein, OTTHUMP00000030141, Putative NF-kappa-B-activating protein 031N, Virus-induced-signaling adapter, interferon beta promoter stimulator protein 1, mitochondrial anti-viral signaling protein, mitochondrial antiviral signaling protein, mitochondrial antiviral-signaling protein, putative NF-kappa-B-activating protein 031N, virus-induced signaling adaptor, virus-induced-signaling adapter, mitochondrial antiviral-signaling protein isoform 1 |
| Other gene names: |
CARDIF, DKFZp547C224, DKFZp666M015, FLJ27482, FLJ31698, FLJ35386, FLJ38051, FLJ41962, IPS-1, IPS1, IPS1, KIAA1271, KIAA1271, MAVS, MGC3260, VISA, VISA, MAVS |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Bands detected at 52 and 75kD, Detects endogenous levels of total human MAVS protein |
| Purification method: |
Affinity Purified by affinity chromatography |
| Form/Appearance: |
100ug/ml BSA and 50% glycerol, 150mM sodium chloride, pH 7, 5, Supplied as a liquid in 10mM sodium HEPES |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage, For maximum recovery of product, For optimal long term storage, Further dilutions can be made in assay buffer, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB), ELISA (EL/EIA) |
| Description: |
By understanding cell signaling, Errors in cellular information processing are responsible for diseases such as cancer, The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, and diabetes, and immunity as well as normal tissue homeostasis, artificial tissues may be created, autoimmunity, diseases may be treated effectively and, theoretically, tissue repair, Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
VISA), Mitochondrial Antiviral Signaling Protein (MAVS |
| Short name: |
VISA) Antibody, Mitochondrial Antiviral Signaling Protein (MAVS |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
VISA) (Antibody to), Mitochondrial Antiviral Signaling Protein (mitochondrial antiviral signaling protein |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CARD domain binding, MAVS and IDBG-49080 and ENSG00000088888 and 57506, Mavs and IDBG-207066 and ENSMUSG00000037523 and 228607, Plasma membranes, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002218 and activation of innate immune response and biological process this GO :0002230 and positive regulation of defense response to virus by host and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005778 and peroxisomal membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0031966 and mitochondrial membrane and cellular component this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032727 and positive regulation of interferon-alpha production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0033160 and positive regulation of protein import into nucleus, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding and also this GO :0050700 : CARD domain binding, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, this GO :0050700 : CARD domain binding, translocation and biological process this GO :0039529 and RIG-I signaling pathway and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0042993 and positive regulation of transcription factor import into nucleus and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045071 and negative regulation of viral genome replication and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050700 and CARD domain binding and molecular function this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051607 and defense response to virus and biological process this GO :0060340 and positive regulation of type I interferon-mediated signaling pathway and biological process this GO :0071360 and cellular response to exogenous dsRNA and biological process this GO :0071651 and positive regulation of chemokine (C-C motif) ligand 5 production and biological process this GO :0071660 and positive regulation of IP-10 production and biological process this GO :1900063 and regulation of peroxisome organization and biological process, 45349 and IDBG-640031 and ENSBTAG00000013545 and 618508, mitochondrial antiviral signaling protein |
| Identity: |
29233 |
| Gene: |
MAVS |
More about : MAVS |
| Long gene name: |
mitochondrial antiviral signaling protein |
| Synonyms: |
VISA KIAA1271 IPS-1 Cardif |
| Synonyms name: |
virus-induced signaling adaptor IFN-B promoter stimulator 1 CARD adaptor inducing IFN-beta |
| Locus: |
20p13 |
| Discovery year: |
2009-04-01 |
| GenBank acession: |
DQ174270 |
| Entrez gene record: |
57506 |
| Pubmed identfication: |
16125763 16153868 |
| RefSeq identity: |
NM_020746 |
| Classification: |
Caspase recruitment domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000031765 |