| known also as: |
Anti-Ubiquitin protein ligase ITCH |
| known also as: |
Ubiquitin protein ligase ITCH |
| known also as: |
Ubiquitin protein ligase ITCH |
| known also as: |
Ubiquitin protein ligase ITCH |
| known also as: |
AIF4 Antibody, AIP4 Antibody, DJ468O1, NAPP1 Antibody, NFE2-associated polypeptide 1 Antibody, 1 Antibody, ITCH Antibody |
| Other names: |
AIP4, Atrophin-1-interacting protein 4, E3 ubiquitin-protein ligase Itchy homolog, E3 ubiquitin-protein ligase Itchy homolog, NAPP1, NFE2-associated polypeptide 1, NFE2-associated polypeptide 1, atrophin-1 interacting protein 4, dJ468O1, itchy E3 ubiquitin protein ligase, itchy E3 ubiquitin protein ligase homolog, 1 (atrophin 1 interacting protein 4 (AIP4)), ITCH protein |
| Other gene names: |
ADMFD, AIF4, AIP4, AIP4, ITCH, Itch, NAPP1, NAPP1, dJ468O1, 1, ITCH |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Mouse, Rat The antibody labels a strong band of ITCH at 108 kDa in PC-ITCH samples and in several cancer cell lines, The antibody does not cross react to any other cellular protein, Human |
| Purification method: |
Affinity Purified |
| Concentration: |
66mg/ml, ~500ug/1000ul Affinity purified antibodies were stabilized at a concentration 0 |
| Storage and shipping: |
Shipping condition- Store productone at +4 degrees Celsius, productone should be stored at -20 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
Ubiquitin protein ligase ITCH |
| Short name: |
Ubiquitin protein ligase ITCH Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Ubiquitin protein ligase itchy E3 ubiquitin protein ligase (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CXCR chemokine receptor binding, ITCH and IDBG-641890 and ENSBTAG00000000308 and 508431, ITCH and IDBG-68143 and ENSG00000078747 and 83737, Itch and IDBG-210517 and ENSMUSG00000027598 and 16396, leucine rich repeat containing receptor signaling pathway and biological process this GO :0042787 and protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process this GO :0043021 and ribonucleoprotein complex binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045236 and CXCR chemokine receptor binding and molecular function this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0046329 and negative regulation of JNK cascade and biological process this GO :0046642 and negative regulation of alpha-beta T cell proliferation and biological process this GO :0046718 and viral entry into host cell and biological process this GO :0050687 and negative regulation of defense response to virus and biological process this GO :0051607 and defense response to virus and biological process this GO :0070423 and nucleotide-binding oli this GO merization domain containing signaling pathway and biological process this GO :0070534 and protein K63-linked ubiquitination and biological process this GO :0070936 and protein K48-linked ubiquitination and biological process this GO :0090085 and regulation of protein deubiquitination and biological process, nuclei, this GO :0000209 and protein polyubiquitination and biological process this GO :0001558 and regulation of cell growth and biological process this GO :0002669 and positive regulation of T cell anergy and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0016020 and membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0035519 and protein K29-linked ubiquitination and biological process this GO :0035872 and nucleotide-binding domain, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding and also this GO :0016874 : ligase activity and also this GO :0043021 : ribonucleoprotein complex binding and also this GO :0045236 : CXCR chemokine receptor binding, this GO :0005515 : protein binding, this GO :0016874 : ligase activity, this GO :0043021 : ribonucleoprotein complex binding, this GO :0045236 : CXCR chemokine receptor binding, itchy E3 ubiquitin protein ligase |
| Identity: |
13890 |
| Gene: |
ITCH |
More about : ITCH |
| Long gene name: |
itchy E3 ubiquitin protein ligase |
| Synonyms gene name: |
itchy (mouse homolog) E3 ubiquitin protein ligase itchy E3 ubiquitin protein ligase homolog (mouse) |
| Synonyms: |
AIP4 |
| Locus: |
20q11, 22 |
| Discovery year: |
2001-04-27 |
| GenBank acession: |
AF095745 |
| Entrez gene record: |
83737 |
| Pubmed identfication: |
11318614 |
| Classification: |
C2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000032300 |
| Locus Specific Databases: |
LRG_354 |