| known also as: |
C-term, Anti-WRN antibody [C3] |
| known also as: |
Anti- [C3], C-term, WRN |
| known also as: |
C-term, WRN antibody [C3] |
| known also as: |
WRN [C3] |
| known also as: |
", ", DKFZp686C2056, RECQ3, RECQL2, RECQL3, RecQ helicase-like, RecQ helicase-like", RecQ helicase-like), RecQ-like type 3", WRN, Werner syndrome, Werner syndrome ATP-dependent helicase, exonuclease WRN, recQ protein-like 2, DNA helicase, Rabbit polyclonal antibody to WRN (Werner syndrome, Werner syndrome |
| Other names: |
DNA helicase, DNA helicase, Exonuclease WRN (EC:3, RecQ helicase-like, RecQ protein-like 2, RecQ-like type 3, RecQ-like type 3, RecQ3, Werner syndrome, Werner syndrome ATP-dependent helicase, Werner syndrome ATP-dependent helicase, exonuclease WRN, recQ protein-like 2, -, -), 1, Werner syndrome ATP-dependent helicase |
| Gene name: |
WRN |
| Other gene names: |
RECQ3, RECQ3, RECQL2, RECQL2, RECQL3, RecQ3, WRN, WRN |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Purification method: |
Purified by antigen-affinity chromatography |
| Form/Appearance: |
Liquid |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Aliquot and store at -20 degrees Celsius, Multiple freeze-thaw cycles should be avoided as they may damage the peptide chains and/or other components and reduce the activity, The product should be kept as concentrated solution |
| Tested for:: |
Western Blot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| French translation: |
anticorps |
| Gene target: |
WRN [C3] C-term |
| Short name: |
WRN antibody [C3] C-term |
| Alternative name: |
RecQ helicase-like (Antibody to) [complement component 3], c terminus, Werner syndrome |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AHUS5 and ARMD9 and ASP and C3a and C3b and CPAMD1 and HEL-S-62p, BT, C3 and IDBG-193788 and ENSMUSG00000024164 and 102642251, C3 and IDBG-21798 and ENSG00000125730 and 718, C5L2 anaphylatoxin chemotactic receptor binding, Extracellular, G-quadruplex DNA binding, RECQ3 and RECQL2 and RECQL3, RecQ helicase-like, WRN and IDBG-16092 and ENSG00000165392 and 7486, WRN and IDBG-628918 and ENSBTAG00000021592 and 505061, Wrn and IDBG-147033 and ENSMUSG00000031583 and 22427, alternative pathway and biological process this GO :0006958 and complement activation, classical pathway and biological process this GO :0007165 and signal transduction and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0010575 and positive regulation vascular endothelial growth factor production and biological process this GO :0010828 and positive regulation of glucose transport and biological process this GO :0010866 and regulation of triglyceride biosynthetic process and biological process this GO :0010884 and positive regulation of lipid storage and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0031715 and C5L2 anaphylatoxin chemotactic receptor binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045745 and positive regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0050776 and regulation of immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072562 and blood microparticle and cellular component this GO :2000427 and positive regulation of apoptotic cell clearance and biological process, complement component 3, nuclei, this GO :0000166 and nucleotide binding and molecular function this GO :0000287 and magnesium ion binding and molecular function this GO :0000403 and Y-form DNA binding and molecular function this GO :0000405 and bubble DNA binding and molecular function this GO :0000723 and telomere maintenance and biological process this GO :0000731 and DNA synthesis involved in DNA repair and biological process this GO :0001302 and replicative cell aging and biological process this GO :0003676 and nucleic acid binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003678 and DNA helicase activity and molecular function this GO :0003824 and catalytic activity and molecular function this GO :0004003 and ATP-dependent DNA helicase activity and molecular function this GO :0004386 and helicase activity and molecular function this GO :0004527 and exonuclease activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005813 and centrosome and cellular component this GO :0006139 and nucleobase-containing compound metabolic process and biological process this GO :0006200 and ATP catabolic process and biological process this GO :0006259 and DNA metabolic process and biological process this GO :0006260 and DNA replication and biological process this GO :0006281 and DNA repair and biological process this GO :0006284 and base-excision repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006310 and DNA recombination and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007568 and aging and biological process this GO :0007569 and cell aging and biological process this GO :0008026 and ATP-dependent helicase activity and molecular function this GO :0008408 and 3'-5' exonuclease activity and molecular function this GO :0009267 and cellular response to starvation and biological process this GO :0009378 and four-way junction helicase activity and molecular function this GO :0010225 and response to UV-C and biological process this GO :0010259 and multicellular organismal aging and biological process this GO :0016887 and ATPase activity and molecular function this GO :0030145 and manganese ion binding and molecular function this GO :0031297 and replication fork processing and biological process this GO :0032066 and nucleolus to nucleoplasm transport and biological process this GO :0032389 and MutLalpha complex and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0032508 and DNA duplex unwinding and biological process this GO :0040009 and regulation of growth rate and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043138 and 3'-5' DNA helicase activity and molecular function this GO :0043140 and ATP-dependent 3'-5' DNA helicase activity and molecular function this GO :0044237 and cellular metabolic process and biological process this GO :0051345 and positive regulation of hydrolase activity and biological process this GO :0051880 and G-quadruplex DNA binding and molecular function this GO :0071480 and cellular response to gamma radiation and biological process this GO :0090305 and nucleic acid phosphodiester bond hydrolysis and biological process, this GO :0000166 : nucleotide binding, this GO :0000166 : nucleotide binding and also this GO :0000287 : magnesium ion binding and also this GO :0000403 : Y-form DNA binding and also this GO :0000405 : bubble DNA binding and also this GO :0003676 : nucleic acid binding and also this GO :0003677 : DNA binding and also this GO :0003678 : DNA helicase activity and also this GO :0003824 : catalytic activity and also this GO :0004003 : ATP-dependent DNA helicase activity and also this GO :0004386 : helicase activity and also this GO :0004527 : exonuclease activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008026 : ATP-dependent helicase activity and also this GO :0008408 : 3'-5' exonuclease activity and also this GO :0009378 : four-way junction helicase activity and also this GO :0016887 : ATPase activity and also this GO :0030145 : manganese ion binding and also this GO :0032403 : protein complex binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043138 : 3'-5' DNA helicase activity and also this GO :0043140 : ATP-dependent 3'-5' DNA helicase activity and also this GO :0051880 : G-quadruplex DNA binding, this GO :0000287 : magnesium ion binding, this GO :0000403 : Y-form DNA binding, this GO :0000405 : bubble DNA binding, this GO :0001798 and positive regulation of type IIa hypersensitivity and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001970 and positive regulation of activation of membrane attack complex and biological process this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006631 and fatty acid metabolic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0006956 and complement activation and biological process this GO :0006957 and complement activation, this GO :0003676 : nucleic acid binding, this GO :0003677 : DNA binding, this GO :0003678 : DNA helicase activity, this GO :0003824 : catalytic activity, this GO :0004003 : ATP-dependent DNA helicase activity, this GO :0004386 : helicase activity, this GO :0004527 : exonuclease activity, this GO :0004866 : endopeptidase inhibitor activity, this GO :0004866 : endopeptidase inhibitor activity and also this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0031715 : C5L2 anaphylatoxin chemotactic receptor binding, this GO :0005102 : receptor binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008026 : ATP-dependent helicase activity, this GO :0008408 : 3'-5' exonuclease activity, this GO :0009378 : four-way junction helicase activity, this GO :0016887 : ATPase activity, this GO :0030145 : manganese ion binding, this GO :0031715 : C5L2 anaphylatoxin chemotactic receptor binding, this GO :0032403 : protein complex binding, this GO :0042803 : protein homodimerization activity, this GO :0043138 : 3'-5' DNA helicase activity, this GO :0043140 : ATP-dependent 3'-5' DNA helicase activity, this GO :0051880 : G-quadruplex DNA binding, 12266, 19562 and IDBG-643930 and ENSBTAG00000017280 and 280677, Werner syndrome |
| Identity: |
12791 |
| Gene: |
WRN |
More about : WRN |
| Long gene name: |
Werner syndrome RecQ like helicase |
| Synonyms gene name: |
Werner syndrome |
| Synonyms: |
RECQL2 RECQ3 |
| Locus: |
8p12 |
| Discovery year: |
1991-08-21 |
| Entrez gene record: |
7486 |
| Pubmed identfication: |
9288107 |
| Classification: |
Exonucleases RecQ like helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000163894 |
| Locus Specific Databases: |
Database of WS-associated WRN mutations LRG_524 |