| known also as: |
Anti-Rabbit Polyclonal (IgG) to Human MCL1 / MCL 1 |
| known also as: |
Rabbit PAb (IgG) to Human MCL1 / MCL 1 |
| known also as: |
Lapin Polyclonal (IgG) to Homo sapiens MCL1 / MCL 1 |
| known also as: |
MCL1 / MCL 1 |
| known also as: |
BCL2L3, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, Bcl2-L-3, EAT, Human MCL1, MCL 1, MCL 1, MCL1, MCL1-ES, MCL1L, MCL1S, Mcl-1, Myeloid cell leukemia ES, TM, Anti-MCL1 / MCL 1 Antibody (aa121-139) IHC-plus |
| Other names: |
Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, Bcl2-L-3, Induced myeloid leukemia cell differentiation protein Mcl-1, bcl-2-like protein 3, bcl-2-related protein EAT/mcl1, induced myeloid leukemia cell differentiation protein Mcl-1, mcl1/EAT, myeloid cell leukemia 1, myeloid cell leukemia ES, myeloid cell leukemia sequence 1 (BCL2-related), induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 |
| Gene name: |
MCL1 |
| Gene name synonims: |
MCL 1 |
| Other gene names: |
BCL2L3, BCL2L3, Bcl2-L-3, EAT, MCL1, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT, MCL1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
BSA, pH 7, sodium azide, 10 mM PBS, 4 |
| Storage and shipping: |
Do not freeze, Store at 2 degree C to 8 degree C degrees |
| Tested for:: |
Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum  |
| Gene target: |
PAb MCL1 / MCL 1 |
| Short name: |
PAb (IgG) MCL1 / MCL 1 Antibody |
| Technique: |
IgGs, antibodies against human proteins, antibodies for, Antibody |
| Isotype: |
IgG |
| Species: |
Humans, Human |
| Alternative name: |
sapiens myeloid cell leukemia sequence 1 (BCL2-related) / MCL 1 (Antibody to), polyclonal (Immunoglobulin G) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BH3 domain binding, MCL1 and IDBG-102145 and ENSG00000143384 and 4170, Mcl1 and IDBG-173221 and ENSMUSG00000038612 and 17210, bcl2-L-3 and BCL2L3 and EAT and Mcl-1 and MCL1-ES and mcl1/EAT and MCL1L and MCL1S and TM, nuclei, this GO :0001709 and cell fate determination and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005829 and cytosol and cellular component this GO :0007275 and multicellular organismal development and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0008637 and apoptotic mitochondrial changes and biological process this GO :0015266 and protein channel activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019725 and cellular homeostasis and biological process this GO :0034097 and response to cytokine and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0051434 and BH3 domain binding and molecular function this GO :0071806 and protein transmembrane transport and biological process this GO :0097136 and Bcl-2 family protein complex and cellular component this GO :0097192 and extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :0097194 and execution phase of apoptosis and biological process this GO :1900118 and negative regulation of execution phase of apoptosis and biological process this GO :2000811 and negative regulation of anoikis and biological process this GO :2001020 and regulation of response to DNA damage stimulus and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :2001243 and negative regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0015266 : protein channel activity and also this GO :0042803 : protein homodimerization activity and also this GO :0046982 : protein heterodimerization activity and also this GO :0051434 : BH3 domain binding, this GO :0015266 : protein channel activity, this GO :0042803 : protein homodimerization activity, this GO :0046982 : protein heterodimerization activity, this GO :0051434 : BH3 domain binding, myeloid cell leukemia sequence 1 (BCL2-related) |
| Identity: |
6943 |
| Gene: |
MCL1 |
More about : MCL1 |
| Long gene name: |
BCL2 family apoptosis regulator |
| Synonyms gene name: |
myeloid cell leukemia sequence 1 (BCL2-related) myeloid cell leukemia 1 |
| Synonyms: |
BCL2L3 Mcl-1 |
| Locus: |
1q21, 2 |
| Discovery year: |
1993-11-09 |
| GenBank acession: |
BC017197 |
| Entrez gene record: |
4170 |
| Pubmed identfication: |
7682708 7835896 |
| RefSeq identity: |
NM_021960 |
| Classification: |
BCL2 family |
| Havana BLAST/BLAT: |
OTTHUMG00000034867 |