| known also as: |
Anti-Sheep Polyclonal (IgG) to Human F8 / FVIII / Factor VIII |
| known also as: |
Ovine PAb (IgG) to Human F8 / FVIII / Factor VIII |
| known also as: |
Ovinae Polyclonal (IgG) to Homo sapiens F8 / FVIII / Factor VIII |
| known also as: |
F8 / FVIII / Factor VIII |
| known also as: |
AHF, Antihemophilic factor, Coagulation factor VIII, Coagulation factor VIIIc, DXS1253E, F8, F8B, F8C, FVIII, FVIII, Factor VIII, Factor VIII, Factor VIII F8B, HEMA, Human F8, Procoagulant component, Anti-F8 / FVIII / Factor VIII Antibody IHC-plus |
| Other names: |
200 kDa isoform, 92 kDa isoform, AHF, Antihemophilic factor, Coagulation factor VIII, Factor VIII B chain, Factor VIIIa heavy chain, Factor VIIIa light chain, Procoagulant componentCleaved into the following 4 chains:Factor VIIIa heavy chain, antihemophilic factor, coagulation factor VIII, coagulation factor VIII, coagulation factor VIIIc, factor VIII F8B, procoagulant component, coagulation factor VIII isoform a |
| Gene name: |
F8 |
| Other gene names: |
AHF, AHF, DXS1253E, F8, F8B, F8C, F8C, FVIII, HEMA, F8 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Sheep |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
No reactivity was observed with von Willebrand Factor, VIII as demonstrated by immunodiffusion and ELISA, Recognizes human F |
| Purification method: |
Ammonium sulfate precipitation |
| Form/Appearance: |
0, 50% glycerol, pH 7, 10 mM HEPES, 15 M sodium chloride, 4 |
| Concentration: |
10 mg/ml |
| Storage and shipping: |
Avoid repeat freeze-thaw cycles, Short term: +Store productone at +4 degrees Celsius, Long term: Store productone at -20 degrees Celsius |
| Tested for:: |
ELISA (EIA), Gel shift, Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, Polyclonals can be used for Western blot, The IgG antibody has 2 , The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , immunohistochemistry on frozen slices or parrafin fixed tissues, mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Group: |
Polyclonals and antibodies |
| Gene target: |
F8 / FVIII / Factor VIII |
| Short name: |
Polyclonal (IgG) F8 / FVIII / Factor VIII Antibody |
| Technique: |
IgGs, Pabs are a collection of immunoglobulin , Polyclonal antibodies , antibodies against human proteins, antibodies for, each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Host: |
Sheep |
| Isotype: |
IgG |
| Species: |
An adult female sheep is referred to as a , Humans, Sheep and goats are also used to produce polyclonals, Sheeps, Some epitopes will also recognize goat proteins, The , a , and a younger sheep as a , (Ovis aries) ELISAs are detecting sheep proteins and antigens, Human, a male as a , castrated , ewe , lamb, male as a , ram, sheep , wether |
| Alternative name: |
procoagulant component / FVIII / Factor VIII (Antibody to), sapiens coagulation factor VIII, ovine polyclonal (Immunoglobulin G) to H |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
AHF and DXS1253E and F8B and F8C and FVIII and HEMA, Extracellular, F8 and IDBG-157124 and ENSMUSG00000031196 and 14069, F8 and IDBG-632125 and ENSBTAG00000010726 and 100271720, F8 and IDBG-92134 and ENSG00000185010 and 2157, intrinsic pathway and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0030168 and platelet activation and biological process this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0055114 and oxidation-reduction process and biological process, oxidoreductase activity, procoagulant component, this GO :0002576 and platelet degranulation and biological process this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005507 and copper ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0006953 and acute-phase response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007596 and blood coagulation and biological process this GO :0007597 and blood coagulation, this GO :0004252 : serine-type endopeptidase activity, this GO :0004252 : serine-type endopeptidase activity and also this GO :0005507 : copper ion binding and also this GO :0005515 : protein binding and also this GO :0016491 : oxidoreductase activity, this GO :0005507 : copper ion binding, this GO :0005515 : protein binding, this GO :0016491 : oxidoreductase activity, coagulation factor VIII |
| Identity: |
3546 |
| Gene: |
F8 |
More about : F8 |
| Long gene name: |
coagulation factor VIII |
| Synonyms gene: |
F8C |
| Synonyms gene name: |
coagulation factor VIII, procoagulant component |
| Synonyms: |
FVIII DXS1253E HEMA |
| Synonyms name: |
Factor VIIIF8B hemophilia A |
| Locus: |
Xq28 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M90707 |
| Entrez gene record: |
2157 |
| Pubmed identfication: |
6438528 3935400 |
| Havana BLAST/BLAT: |
OTTHUMG00000022688 |
| Locus Specific Databases: |
HAMSTeRS: The Haemophilia A Mutation, Resource Site Mental Retardation database LRG_555 , Structure, Test & |