| Also known as: |
F8 / FVIII / Factor VIII |
| Other names: |
200 kDa isoform, 92 kDa isoform, AHF, Antihemophilic factor, Coagulation factor VIII, Factor VIII B chain, Factor VIIIa heavy chain, Factor VIIIa light chain, Procoagulant componentCleaved into the following 4 chains:Factor VIIIa heavy chain, antihemophilic factor, coagulation factor VIII, coagulation factor VIII, coagulation factor VIIIc, factor VIII F8B, procoagulant component, coagulation factor VIII isoform a |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
F8 |
| Other gene names: |
AHF, AHF, DXS1253E, F8, F8B, F8C, F8C, FVIII, HEMA, F8 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Does not cross-react with von Willebrand factor, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Recognizes full-length human Factor VIII |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
pH 7, 4, PBS |
| Concentration: |
73 mg/ml |
| Storage and shipping: |
Aliquot to avoid freeze/thaw cycles, or -70 degree C, Store the antibody should be stored at -20 degrees Celsius |
| Tested applications:: |
Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal (IgG1) F8 / FVIII / Factor VIII |
| Short name: |
Mouse Monoclonal (IgG1) F8 / FVIII / Factor VIII Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
procoagulant component / FVIII / Factor VIII (Antibody to), sapiens coagulation factor VIII, Mouse monoclonal (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AHF and DXS1253E and F8B and F8C and FVIII and HEMA, Extracellular, F8 and IDBG-157124 and ENSMUSG00000031196 and 14069, F8 and IDBG-632125 and ENSBTAG00000010726 and 100271720, F8 and IDBG-92134 and ENSG00000185010 and 2157, intrinsic pathway and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0030168 and platelet activation and biological process this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0055114 and oxidation-reduction process and biological process, oxidoreductase activity, procoagulant component, this GO :0002576 and platelet degranulation and biological process this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005507 and copper ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0006953 and acute-phase response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007596 and blood coagulation and biological process this GO :0007597 and blood coagulation, this GO :0004252 : serine-type endopeptidase activity, this GO :0004252 : serine-type endopeptidase activity and also this GO :0005507 : copper ion binding and also this GO :0005515 : protein binding and also this GO :0016491 : oxidoreductase activity, this GO :0005507 : copper ion binding, this GO :0005515 : protein binding, this GO :0016491 : oxidoreductase activity, coagulation factor VIII |
| Identity: |
3546 |
| Gene: |
F8 |
More about : F8 |
| Long gene name: |
coagulation factor VIII |
| Synonyms gene: |
F8C |
| Synonyms gene name: |
coagulation factor VIII, procoagulant component |
| Synonyms: |
FVIII DXS1253E HEMA |
| Synonyms name: |
Factor VIIIF8B hemophilia A |
| Locus: |
Xq28 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M90707 |
| Entrez gene record: |
2157 |
| Pubmed identfication: |
6438528 3935400 |
| Havana BLAST/BLAT: |
OTTHUMG00000022688 |
| Locus Specific Databases: |
HAMSTeRS: The Haemophilia A Mutation, Resource Site Mental Retardation database LRG_555 , Structure, Test & |