| known also as: |
Anti-Rabbit Polyclonal (IgG) to Human PMS2 |
| known also as: |
Rabbit PAb (IgG) to Human PMS2 |
| known also as: |
Lapin Polyclonal (IgG) to Homo sapiens PMS2 |
| known also as: |
PMS2 |
| known also as: |
HNPCC4, H_DJ0042M02, Human PMS2, PMS1 protein homolog 2, PMS2, PMS2CL, PMSL2, 9, Anti-PMS2 Antibody (aa125-174) IHC-plus |
| Other names: |
DNA mismatch repair protein PMS2, DNA mismatch repair protein PMS2, H_DJ0042M02, Mismatch repair endonuclease PMS2, PMS1 protein homolog 2, PMS1 protein homolog 2, PMS2 postmeiotic segregation increased 2 (S, cerevisiae), mismatch repair endonuclease PMS2, 9, mismatch repair endonuclease PMS2 isoform a |
| Gene name: |
PMS2 |
| Other gene names: |
HNPCC4, PMS2, PMS2CL, PMSL2, PMSL2, PMS2 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
PMS2/PMS2CL Antibody detects endogenous levels of total PMS2/PMS2CL protein |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
0, 150 mM sodium chloride, 50% glycerol, Ca2+), pH 7, 02% sodium azide, 4, PBS (without Mg2+ |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
avoid freeze thaw cycles, long term aliquot and store productone should be stored at -20 degrees Celsius, Short term Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Gene target: |
PAb PMS2 |
| Short name: |
PAb (IgG) PMS2 Antibody |
| Technique: |
IgGs, antibodies against human proteins, antibodies for, Antibody |
| Isotype: |
IgG |
| Species: |
Humans, Human |
| Alternative name: |
cerevisiae) (Antibody to), sapiens PMS2 postmeiotic segregation increased 2 (S, polyclonal (Immunoglobulin G) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
HNPCC4 and PMS2CL and PMSL2, MutSalpha complex binding, PMS2 and IDBG-640975 and ENSBTAG00000007364 and 527039, PMS2 and IDBG-7921 and ENSG00000122512 and 5395, Pms2 and IDBG-259679 and ENSMUSG00000079109 and 18861, cerevisiae), nuclei, this GO :0003677 and DNA binding and molecular function this GO :0003697 and single-stranded DNA binding and molecular function this GO :0004519 and endonuclease activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006281 and DNA repair and biological process this GO :0006298 and mismatch repair and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0016446 and somatic hypermutation of immunoglobulin genes and biological process this GO :0016447 and somatic recombination of immunoglobulin gene segments and biological process this GO :0016887 and ATPase activity and molecular function this GO :0030983 and mismatched DNA binding and molecular function this GO :0032138 and single base insertion or deletion binding and molecular function this GO :0032300 and mismatch repair complex and cellular component this GO :0032389 and MutLalpha complex and cellular component this GO :0032407 and MutSalpha complex binding and molecular function this GO :0042493 and response to drug and biological process this GO :0090305 and nucleic acid phosphodiester bond hydrolysis and biological process, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003697 : single-stranded DNA binding and also this GO :0004519 : endonuclease activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016887 : ATPase activity and also this GO :0030983 : mismatched DNA binding and also this GO :0032138 : single base insertion or deletion binding and also this GO :0032407 : MutSalpha complex binding, this GO :0003697 : single-stranded DNA binding, this GO :0004519 : endonuclease activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016887 : ATPase activity, this GO :0030983 : mismatched DNA binding, this GO :0032138 : single base insertion or deletion binding, this GO :0032407 : MutSalpha complex binding, PMS2 postmeiotic segregation increased 2 (S |
| Identity: |
9122 |
| Gene: |
PMS2 |
More about : PMS2 |
| Long gene name: |
PMS1 homolog 2, mismatch repair system component |
| Synonyms gene: |
PMSL2 |
| Synonyms gene name: |
cerevisiae) 2 PMS2 postmeiotic segregation increased 2 (S, cerevisiae) PMS1 homolog 2, mismatch repair protein , postmeiotic segregation increased (S |
| Synonyms: |
H_DJ0042M02, 9 HNPCC4 MLH4 |
| Locus: |
7p22, 1 |
| Discovery year: |
1994-12-13 |
| Entrez gene record: |
5395 |
| Pubmed identfication: |
8072530 |
| RefSeq identity: |
NM_000535 |
| Classification: |
MutL homologs |
| Havana BLAST/BLAT: |
OTTHUMG00000023135 |
| Locus Specific Databases: |
HNPCC Colon cancer gene variant databases PMS2 database at LOVD-China LRG_161 , Hereditary Non-Polyposis Colorectal Cancer |