| Long name: |
262, 47) Monoclonal Antibody, TIMP2 (1554CT494 |
| Also known as: |
262, 47) Monoclonal Antibody, TIMP2 (1554CT494 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TIMP2 |
| Specificity: |
This is a highly specific antibody against TIMP2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
1554CT494, 47, 262 |
| Source: |
This TIMP2 antibody is generated from a mouse immunized with arecombinant protein of human TIMP2 |
| Gene ID number: |
7077 |
| Swiss Prot: |
P16035 |
| Tested Applications: |
FCM, IF, IHC-P, WB |
| Recommended dilutions: |
FC(1:25), WB(1:500), IF(1:25) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Known to act on MMP-1, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CSC-21K, Metalloproteinase inhibitor 2, TIMP-2, TIMP2, Tissue inhibitor of metalloproteinases 2, DDC8 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
262, 47) Monoclonal, TIMP2 (1554CT494 |
| Short name: |
262, 47) Monoclonal Antibody, TIMP2 (1554CT494 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
262, 47) monoclonal (Antibody to), TIMP metallopeptidase inhibitor 2 (1554CT494 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CSC-21K and DDC8, Extracellular, TIMP2 and IDBG-70963 and ENSG00000035862 and 7077, Timp2 and IDBG-214632 and ENSMUSG00000017466 and 21858, metal ion binding, this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005604 and basement membrane and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007417 and central nervous system development and biological process this GO :0007568 and aging and biological process this GO :0008047 and enzyme activator activity and molecular function this GO :0008152 and metabolic process and biological process this GO :0008191 and metalloendopeptidase inhibitor activity and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009986 and cell surface and cellular component this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030426 and growth cone and cellular component this GO :0030814 and regulation of cAMP metabolic process and biological process this GO :0032487 and regulation of Rap protein signal transduction and biological process this GO :0034097 and response to cytokine and biological process this GO :0042493 and response to drug and biological process this GO :0043005 and neuron projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043408 and regulation of MAPK cascade and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045664 and regulation of neuron differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045762 and positive regulation of adenylate cyclase activity and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0045930 and negative regulation of mitotic cell cycle and biological process this GO :0046580 and negative regulation of Ras protein signal transduction and biological process this GO :0046872 and metal ion binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071310 and cellular response to organic substance and biological process, this GO :0005178 : integrin binding, this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0008047 : enzyme activator activity and also this GO :0008191 : metalloendopeptidase inhibitor activity and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0008047 : enzyme activator activity, this GO :0008191 : metalloendopeptidase inhibitor activity, this GO :0046872 : metal ion binding, 52974 and IDBG-642791 and ENSBTAG00000010899 and 282093, TIMP metallopeptidase inhibitor 2 |
| Identity: |
11821 |
| Gene: |
TIMP2 |
More about : TIMP2 |
| Long gene name: |
TIMP metallopeptidase inhibitor 2 |
| Synonyms gene name: |
tissue inhibitor of metalloproteinase 2 |
| Synonyms: |
CSC-21K |
| Locus: |
17q25, 3 |
| Discovery year: |
1992-06-18 |
| Entrez gene record: |
7077 |
| Pubmed identfication: |
1427908 |
| RefSeq identity: |
NM_003255 |
| Classification: |
Tissue inhibitor of metallopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000154517 |