| Also known as: |
TIMP2 |
| Other names: |
CSC-21K, KIAA1731 N-terminal like protein, Metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, TIMP-2, Tissue inhibitor of metalloproteinases 2, metalloproteinase inhibitor 2, tissue inhibitor of metalloproteinase 2, tissue inhibitor of metalloproteinases 2, metalloproteinase inhibitor 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
TIMP2 |
| Other gene names: |
CSC-21K, DDC8, KIAA1731NL, TIMP-2, TIMP2, TIMP2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
F27P3A4 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Bovine, Chicken, Dog, Due to limited knowledge and inability for testing each and every species, Gorilla, Guinea pig, Hamster, Horse, Human (Homo sapiens), Monkey, Mouse (Mus musculus), Pig, Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus), Sheep, Zebrafish <, the reactivity of the antibody may extend to other species which are not listed hereby, /b>, Gibbon, Predicted Reactivity: <, Xenopus (at least 90% immunogen sequence identity), b> |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Ovalbumin-conjugated synthetic Peptide DSGNDIYGNPI |
| Purification method: |
Affinity Purified |
| Form/Appearance: |
0, pH 7, 09% sodium azide, 2, Phosphate-buffered solution |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Freezing of the antibody is not recommended, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ F27P3A4] (IgG2a) TIMP2 |
| Short name: |
Mouse Monoclonal [clone F27P3A4] (IgG2a) TIMP2 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens TIMP metallopeptidase inhibitor 2 (Antibody to), Mouse monoclonal [clonality F27P3A4] (IgG2a) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CSC-21K and DDC8, Extracellular, TIMP2 and IDBG-70963 and ENSG00000035862 and 7077, Timp2 and IDBG-214632 and ENSMUSG00000017466 and 21858, metal ion binding, this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005604 and basement membrane and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007417 and central nervous system development and biological process this GO :0007568 and aging and biological process this GO :0008047 and enzyme activator activity and molecular function this GO :0008152 and metabolic process and biological process this GO :0008191 and metalloendopeptidase inhibitor activity and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009986 and cell surface and cellular component this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030426 and growth cone and cellular component this GO :0030814 and regulation of cAMP metabolic process and biological process this GO :0032487 and regulation of Rap protein signal transduction and biological process this GO :0034097 and response to cytokine and biological process this GO :0042493 and response to drug and biological process this GO :0043005 and neuron projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043408 and regulation of MAPK cascade and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045664 and regulation of neuron differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045762 and positive regulation of adenylate cyclase activity and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0045930 and negative regulation of mitotic cell cycle and biological process this GO :0046580 and negative regulation of Ras protein signal transduction and biological process this GO :0046872 and metal ion binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071310 and cellular response to organic substance and biological process, this GO :0005178 : integrin binding, this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0008047 : enzyme activator activity and also this GO :0008191 : metalloendopeptidase inhibitor activity and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0008047 : enzyme activator activity, this GO :0008191 : metalloendopeptidase inhibitor activity, this GO :0046872 : metal ion binding, 52974 and IDBG-642791 and ENSBTAG00000010899 and 282093, TIMP metallopeptidase inhibitor 2 |
| Identity: |
11821 |
| Gene: |
TIMP2 |
More about : TIMP2 |
| Long gene name: |
TIMP metallopeptidase inhibitor 2 |
| Synonyms gene name: |
tissue inhibitor of metalloproteinase 2 |
| Synonyms: |
CSC-21K |
| Locus: |
17q25, 3 |
| Discovery year: |
1992-06-18 |
| Entrez gene record: |
7077 |
| Pubmed identfication: |
1427908 |
| RefSeq identity: |
NM_003255 |
| Classification: |
Tissue inhibitor of metallopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000154517 |