| Long name: |
Syk (12E3) Monoclonal Antibody |
| Also known as: |
Syk (12E3) Monoclonal Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Syk |
| Specificity: |
This is a highly specific antibody against Syk |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
12000 |
| Source: |
Synthetic peptide |
| Gene ID number: |
6850 |
| Swiss Prot: |
P43405 |
| Tested Applications: |
IP, WB |
| Recommended dilutions: |
000) IP (2 ul), WB (1:1 |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Activated and autophosphorylated Syk then phosphorylates its specific substrates including other enzymes and adaptor proteins, BCR, Fc receptors) containing immunoreceptor tyrosine-based activation motifs (ITAMs) to which it binds using its tandem SH2 domains, In hematopoietic cells such as B and T lymphocytes, Spleen tyrosine kinase, Syk is involved in the proximal signaling downstream of activated immunoreceptors (e, TCR, differentiation, is expressed in a wide range of hematopoietic and non-hematopoietic cells and plays a key role in adaptive immune system, macrophages and platelets, mast cells, natural killer cells, orchestrating a complex series of cellular responses such as cell proliferation, receptor-mediated phagocytosis, survival and phagocytosis, which is the immunoreceptor (B cell receptor and Fc-receptors) signaling pathways including Fc&gamma, Syk, g |
| Purification method: |
Ammonium sulfate precipitation |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
SYK, Spleen tyrosine kinase, Tyrosine-protein kinase SYK, p72-Syk |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
Syk (12E3) Monoclonal |
| Short name: |
Syk (12E3) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
spleen tyrosine kinase (12E3) monoclonal (Antibody to) |
| Alternative technique: |
antibodies |