| Also known as: |
ABCB1 / MDR1 / P Glycoprotein |
| Other names: |
ATP-binding cassette, ATP-binding cassette sub-family B member 1, CD_antigen: CD243, Multidrug resistance protein 1, P-glycoprotein 1, P-glycoprotein 1, colchicin sensitivity, doxorubicin resistance, member 1, multidrug resistance protein 1, sub-family B (MDR/TAP), multidrug resistance protein 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ABCB1 |
| Gene name synonims: |
P Glycoprotein, MDR1 |
| Other gene names: |
ABC20, ABCB1, CD243, CLCS, GP170, MDR1, MDR1, P-GP, PGY1, PGY1, ABCB1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
JSB-1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Cross-reacts with Chinese hamster, No cross-reactivity with mouse or rat, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, including cell lines derived from lung, ovaries and B cell lymphomas, the expression of which is strongly correlated with the degree of multi-drug-resistance (MDR) derived MDR cell lines and human MDR cell lines, The antibody JSB-1 reacts with a conserved cytoplasmic epitope of the plasma membrane-associated 170-180 kD glycoprotein |
| Purification method: |
Tissue culture supernatant |
| Form/Appearance: |
0, 1% BSA, 1% sodium azide, Tissue culture supernatant |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Flow Cytometry (FC/FACS), IHC - Frozen), Western Blot (WB), Immunohistochemistry (IHC - Paraffin |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ JSB-1] (IgG1) ABCB1 / MDR1 / P Glycoprotein |
| Short name: |
Mouse Monoclonal [clone JSB-1] (IgG1) ABCB1 / MDR1 / P Glycoprotein Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens ABCB1 / MDR1 / P Glycoprotein (Antibody to), Mouse monoclonal [clonality JSB-1] (IgG1) to H |
| Alternative technique: |
antibodies |
| Identity: |
40 |
| Gene: |
ABCB1 |
More about : ABCB1 |
| Long gene name: |
ATP binding cassette subfamily B member 1 |
| Synonyms gene: |
PGY1 MDR1 CLCS |
| Synonyms gene name: |
colchicin sensitivity ATP-binding cassette, member 1 , sub-family B (MDR/TAP) |
| Synonyms: |
P-gp CD243 GP170 ABC20 |
| Synonyms name: |
multidrug resistance protein 1 |
| Locus: |
7q21, 12 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M14758 |
| Entrez gene record: |
5243 |
| Pubmed identfication: |
3027054 |
| RefSeq identity: |
NM_000927 |
| Classification: |
CD molecules ATP binding cassette subfamily B |
| Havana BLAST/BLAT: |
OTTHUMG00000023393 |