| Also known as: |
MDM4 / MDMX |
| Other names: |
Double minute 4 protein, MDM4, MDM4 protein variant G, MDM4 protein variant Y, MDM4-related protein 1, Mdm2-like p53-binding protein, Mdm4 p53 binding protein homolog, Protein Mdm4, Protein Mdmx, double minute 4, human homolog of, mdm2-like p53-binding protein, p53 regulator, p53-binding protein, p53-binding protein Mdm4, protein Mdm4, protein Mdmx, protein Mdm4 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MDM4 |
| Gene name synonims: |
MDMX |
| Other gene names: |
HDMX, MDM4, MDMX, MDMX, MRP1, MDM4 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
2D10F4 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human MDM4 |
| Purification method: |
Ascites |
| Form/Appearance: |
0, 03% sodium azide, Ascites fluid |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
ELISA (EIA), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 2D10F4] (IgG1) MDM4 / MDMX |
| Short name: |
Mouse Monoclonal [clone 2D10F4] (IgG1) MDM4 / MDMX Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens Mdm4 p53 binding protein homolog (mouse) / MDMX (Antibody to), Mouse monoclonal [clonality 2D10F4] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, HDMX and MDMX and MRP1, MDM4 and IDBG-106054 and ENSG00000198625 and 4194, Mdm4 and IDBG-192393 and ENSMUSG00000054387 and 102641776, enzyme binding, nuclei, signal transduction by p53 class mediator and biological process this GO :0042177 and negative regulation of protein catabolic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045023 and G0 to G1 transition and biological process this GO :0050821 and protein stabilization and biological process this GO :0071157 and negative regulation of cell cycle arrest and biological process this GO :0071456 and cellular response to hypoxia and biological process, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0019899 and enzyme binding and molecular function this GO :0030330 and DNA damage response, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0019899 : enzyme binding, this GO :0008270 : zinc ion binding, this GO :0019899 : enzyme binding, 17248, 36413 and IDBG-628663 and ENSBTAG00000006255 and 100138492, 514225, Mdm4 p53 binding protein homolog (mouse) |
| Identity: |
6974 |
| Gene: |
MDM4 |
More about : MDM4 |
| Long gene name: |
MDM4, p53 regulator |
| Synonyms gene name: |
human homolog of, mouse double minute 4, p53 binding protein (mouse) Mdm4 p53 binding protein homolog (mouse) , p53-binding protein Mdm4, transformed 3T3 cell double minute 4 |
| Synonyms: |
MDMX HDMX |
| Locus: |
1q32, 1 |
| Discovery year: |
1997-09-05 |
| GenBank acession: |
AF007111 |
| Entrez gene record: |
4194 |
| Pubmed identfication: |
9226370 14660608 |
| RefSeq identity: |
NM_002393 |
| Havana BLAST/BLAT: |
OTTHUMG00000035877 |