| Also known as: |
MAP4K1 / HPK1 |
| Other names: |
Hematopoietic progenitor kinase, MAPK/ERK kinase kinase kinase 1, MAPK/ERK kinase kinase kinase 1, MEK kinase kinase 1, MEK kinase kinase 1, MEKKK 1, MEKKK 1, Mitogen-activated protein kinase kinase kinase kinase 1, hematopoietic progenitor kinase 1, mitogen-activated protein kinase kinase kinase kinase 1, mitogen-activated protein kinase kinase kinase kinase 1, mitogen-activated protein kinase kinase kinase kinase 1 isoform 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MAP4K1 |
| Gene name synonims: |
HPK1 |
| Other gene names: |
HPK1, HPK1, MAP4K1, MEK kinase kinase 1, MEKKK 1, MAP4K1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, l |
| Clone: |
2A1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Ammonium sulfate precipitation |
| Form/Appearance: |
0, 0, Sourced in Ascites, and 50% glycerol, 01% BSA, 03% sodium azide, 15M NaCl, HEPES with 0 |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 2A1] (IgG1, l) MAP4K1 / HPK1 |
| Short name: |
Mouse Monoclonal [clone 2A1] (IgG1, l) MAP4K1 / HPK1 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens mitogen-activated protein phosphorylation catalyst kinase phosphorylation catalyst kinase 1 / HPK1 (Antibody to), Mouse monoclonal [clonality 2A1] (IgG1, l) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
HPK1, MAP4K1 and IDBG-49296 and ENSG00000104814 and 11184, MAP4K1 and IDBG-637177 and ENSBTAG00000021145 and 522002, Map4k1 and IDBG-165254 and ENSMUSG00000037337 and 26411, Plasma membranes, this GO :0000185 and activation of MAPKKK activity and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005083 and small GTPase regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0006468 and protein phosphorylation and biological process this GO :0006950 and response to stress and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0008283 and cell proliferation and biological process this GO :0008349 and MAP kinase kinase kinase kinase activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005083 : small GTPase regulator activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008349 : MAP kinase kinase kinase kinase activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005083 : small GTPase regulator activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008349 : MAP kinase kinase kinase kinase activity, this GO :0016772 : transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0050790 and regulation of catalytic activity and biological process, mitogen-activated protein kinase kinase kinase kinase 1 |
| Identity: |
6863 |
| Gene: |
MAP4K1 |
More about : MAP4K1 |
| Long gene name: |
mitogen-activated protein kinase kinase kinase kinase 1 |
| Synonyms: |
HPK1 |
| Synonyms name: |
hematopoietic progenitor kinase 1 |
| Locus: |
19q13, 1-q13, 4 |
| Discovery year: |
1999-09-07 |
| GenBank acession: |
U66464 |
| Entrez gene record: |
11184 |
| Pubmed identfication: |
8824585 |
| RefSeq identity: |
NM_001042600 |
| Classification: |
Mitogen-activated protein kinase kinase kinase kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000180863 |