| Also known as: |
BTK |
| Other names: |
ATK, Agammaglobulinemia tyrosine kinase, B-cell progenitor kinase, B-cell progenitor kinase, BPK, Bruton agammaglobulinemia tyrosine kinase, Bruton tyrosine kinase, Tyrosine-protein kinase BTK, agammaglobulinaemia tyrosine kinase, dominant-negative kinase-deficient Brutons tyrosine kinase, truncated Bruton agammaglobulinemia tyrosine kinase, tyrosine-protein kinase BTK, tyrosine-protein kinase BTK isoform (lacking exon 14), tyrosine-protein kinase BTK isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
BTK |
| Other gene names: |
AGMX1, AGMX1, AT, ATK, ATK, ATK, BPK, BPK, BPK, BTK, IMD1, PSCTK1, XLA, BTK |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Ammonium sulfate precipitation |
| Form/Appearance: |
0, 0, and 50% glycerol, 01% BSA, 03% sodium azide, 15M NaCl, HEPES with 0 |
| Storage and shipping: |
Long term storage of the antibody should be done at -20 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal (IgG1, k) BTK |
| Short name: |
Mouse Monoclonal (IgG1, k) BTK Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens Bruton agammaglobulinemia tyrosine kinase (Antibody to), Mouse monoclonal (IgG1, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AGMX1 and AT and ATK and BPK and IMD1 and PSCTK1 and XLA, BTK and IDBG-633447 and ENSBTAG00000019250 and 533459, BTK and IDBG-79651 and ENSG00000010671 and 695, Btk and IDBG-171427 and ENSMUSG00000031264 and 12229, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0007498 and mesoderm development and biological process this GO :0010033 and response to organic substance and biological process this GO :0016772 and transferase activity, nuclei, phosphatidylinositol-3, this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002250 and adaptive immune response and biological process this GO :0002553 and histamine secretion by mast cell and biological process this GO :0002721 and regulation of B cell cytokine production and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002902 and regulation of B cell apoptotic process and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005547 and phosphatidylinositol-3, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0005547 : phosphatidylinositol-3, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005547 : phosphatidylinositol-3, this GO :0016772 : transferase activity, this GO :0042802 : identical protein binding, this GO :0046872 : metal ion binding, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042802 : identical protein binding and also this GO :0046872 : metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019722 and calcium-mediated signaling and biological process this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034614 and cellular response to reactive oxygen species and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042113 and B cell activation and biological process this GO :0042629 and mast cell granule and cellular component this GO :0042802 and identical protein binding and molecular function this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045579 and positive regulation of B cell differentiation and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048469 and cell maturation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0071226 and cellular response to molecule of fungal origin and biological process this GO :0097190 and apoptotic signaling pathway and biological process, 4, 4, 4, 5-trisphosphate binding, 5-trisphosphate binding and also this GO :0016772 : transferase activity, 5-trisphosphate binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, Bruton agammaglobulinemia tyrosine kinase |
| Identity: |
1133 |
| Gene: |
BTK |
More about : BTK |
| Long gene name: |
Bruton tyrosine kinase |
| Synonyms gene: |
AGMX1 IMD1 |
| Synonyms gene name: |
Bruton agammaglobulinemia tyrosine kinase |
| Synonyms: |
ATK XLA PSCTK1 |
| Synonyms name: |
Bruton', s tyrosine kinase |
| Locus: |
Xq22, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
AK057105 |
| Entrez gene record: |
695 |
| Pubmed identfication: |
8380905 |
| RefSeq identity: |
NM_000061 |
| Classification: |
Pleckstrin homology domain containing SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000022022 |
| Locus Specific Databases: |
BTK base: Mutation registry for X-linked agammaglobulinemia Mental Retardation database LRG_128 |