| Long name: |
Recombinant Human Tyrosine-protein kinase BTK (Btk) |
| Alternative names: |
ATK, Agammaglobulinemia tyrosine kinase, B-cell progenitor kinase, B-cell progenitor kinase, BPK, Bruton agammaglobulinemia tyrosine kinase, Bruton tyrosine kinase, Tyrosine-protein kinase BTK, agammaglobulinaemia tyrosine kinase, dominant-negative kinase-deficient Brutons tyrosine kinase, truncated Bruton agammaglobulinemia tyrosine kinase, tyrosine-protein kinase BTK, tyrosine-protein kinase BTK isoform (lacking exon 14), tyrosine-protein kinase BTK isoform 1 |
| Gene name: |
BTK |
| Other gene names: |
AGMX1, AGMX1, AT, ATK, ATK, ATK, BPK, BPK, BPK, BTK, IMD1, PSCTK1, XLA, BTK |
| General description: |
All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, Tyrosine-protein kinase BTK (Btk) is a recombinant protein expressed in Mammalian Cell |
| Product category: |
Recombinant Proteins |
| Expression system: |
Mammalian Cell |
| Available also expressed in:: |
Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity: |
Greater than 90% (determined by SDS-PAGE) |
| Form: |
Lyophilized protein |
| Storage: |
Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications: |
IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target: |
Tyrosine-protein kinase BTK (Btk) |
| Short name: |
Tyrosine-protein kinase BTK (Btk) |
| Species: |
Humans, Human |
| Alternative name: |
sapiens Tyrosine-protein phosphorylation catalyst Bruton agammaglobulinemia tyrosine kinase (Bruton agammaglobulinemia tyrosine kinase), H |
| Alternative to gene target: |
AGMX1 and AT and ATK and BPK and IMD1 and PSCTK1 and XLA, BTK and IDBG-633447 and ENSBTAG00000019250 and 533459, BTK and IDBG-79651 and ENSG00000010671 and 695, Btk and IDBG-171427 and ENSMUSG00000031264 and 12229, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0007498 and mesoderm development and biological process this GO :0010033 and response to organic substance and biological process this GO :0016772 and transferase activity, nuclei, phosphatidylinositol-3, this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002250 and adaptive immune response and biological process this GO :0002553 and histamine secretion by mast cell and biological process this GO :0002721 and regulation of B cell cytokine production and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002902 and regulation of B cell apoptotic process and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005547 and phosphatidylinositol-3, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0005547 : phosphatidylinositol-3, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005547 : phosphatidylinositol-3, this GO :0016772 : transferase activity, this GO :0042802 : identical protein binding, this GO :0046872 : metal ion binding, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042802 : identical protein binding and also this GO :0046872 : metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019722 and calcium-mediated signaling and biological process this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034614 and cellular response to reactive oxygen species and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042113 and B cell activation and biological process this GO :0042629 and mast cell granule and cellular component this GO :0042802 and identical protein binding and molecular function this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045579 and positive regulation of B cell differentiation and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048469 and cell maturation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0071226 and cellular response to molecule of fungal origin and biological process this GO :0097190 and apoptotic signaling pathway and biological process, 4, 4, 4, 5-trisphosphate binding, 5-trisphosphate binding and also this GO :0016772 : transferase activity, 5-trisphosphate binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, Bruton agammaglobulinemia tyrosine kinase |
| Identity: |
1133 |
| Gene: |
BTK |
More about : BTK |
| Long gene name: |
Bruton tyrosine kinase |
| Synonyms gene: |
AGMX1 IMD1 |
| Synonyms gene name: |
Bruton agammaglobulinemia tyrosine kinase |
| Synonyms: |
ATK XLA PSCTK1 |
| Synonyms name: |
Bruton', s tyrosine kinase |
| Locus: |
Xq22, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
AK057105 |
| Entrez gene record: |
695 |
| Pubmed identfication: |
8380905 |
| RefSeq identity: |
NM_000061 |
| Classification: |
Pleckstrin homology domain containing SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000022022 |
| Locus Specific Databases: |
BTK base: Mutation registry for X-linked agammaglobulinemia Mental Retardation database LRG_128 |