| Also known as: |
TWIST2 |
| Other names: |
Dermis-expressed protein 1, Dermo-1, Twist-related protein 2, dermis expressed 1, dermis-expressed protein 1, dermo-1, twist basic helix-loop-helix transcription factor 2, twist homolog 2, twist-related protein 2, twist-related protein 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
TWIST2 |
| Other gene names: |
Dermo-1, Dermo1, Dermo1, Twist2, bHLHa39, Twist2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Clone: |
3C8 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
Sourced in Ascites, pH 7, 4, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
We strongly recommend to avoid freeze/thaw cycles in order to keep the activity of the antibody maximally unchanged, the antibody should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 3C8] (IgG1, k) TWIST2 |
| Short name: |
Mouse Monoclonal [clone 3C8] (IgG1, k) TWIST2 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens twist homolog 2 (Drosophila) (Antibody to), Mouse monoclonal [clonality 3C8] (IgG1, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0048701 and embryonic cranial skeleton morphogenesis and biological process this GO :0060325 and face morphogenesis and biological process this GO :0061303 and cornea development in camera-type eye and biological process, TWIST2 and IDBG-310754 and ENSG00000233608 and 117581, TWIST2 and IDBG-642241 and ENSBTAG00000021444 and 540060, Twist2 and IDBG-181549 and ENSMUSG00000007805 and 13345, nuclei, protein dimerization activity, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001076 and RNA polymerase II transcription factor binding transcription factor activity and molecular function this GO :0001649 and osteoblast differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010838 and positive regulation of keratinocyte proliferation and biological process this GO :0019904 and protein domain specific binding and molecular function this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043392 and negative regulation of DNA binding and biological process this GO :0044092 and negative regulation of molecular function and biological process this GO :0045638 and negative regulation of myeloid cell differentiation and biological process this GO :0045668 and negative regulation of osteoblast differentiation and biological process this GO :0045892 and negative regulation of transcription, this GO :0001076 : RNA polymerase II transcription factor binding transcription factor activity, this GO :0001076 : RNA polymerase II transcription factor binding transcription factor activity and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0019904 : protein domain specific binding and also this GO :0046983 : protein dimerization activity, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0019904 : protein domain specific binding, this GO :0046983 : protein dimerization activity, twist homolog 2 (Drosophila) |
| Identity: |
20670 |
| Gene: |
TWIST2 |
More about : TWIST2 |
| Long gene name: |
twist family bHLH transcription factor 2 |
| Synonyms gene name: |
twist homolog 2 (Drosophila) twist basic helix-loop-helix transcription factor 2 |
| Synonyms: |
DERMO1 Dermo-1 bHLHa39 |
| Locus: |
2q37, 3 |
| Discovery year: |
2003-03-25 |
| GenBank acession: |
BC017907 |
| Entrez gene record: |
117581 |
| Pubmed identfication: |
7589808 9061034 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000152836 |