| Also known as: |
SELPLG / PSGL-1 / CD162 |
| Other names: |
CD_antigen: CD162, P-selectin glycoprotein ligand 1, P-selectin glycoprotein ligand 1, Selectin P ligand, cutaneous lymphocyte-associated associated antigen, selectin P ligand, P-selectin glycoprotein ligand 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SELPLG |
| Gene name synonims: |
CD162, PSGL-1 |
| Other gene names: |
CD162, CLA, PSGL-1, PSGL-1, PSGL1, SELPLG, SELPLG |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
10 (PL2), 5D8, 8, 12 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD162 is the major counter receptor for P-selectin and is involved in neutrophil attachment and rolling to endothelium, In peripheral blood CD162 is expressed by monocytes, Is not a blocking antibody, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, T cells and some B cells, This particular antibody might cross react with speacies outside of the listed ones, a 120kD molecule also known as P-Selectin Glycoprotein Ligand I (PSGL-1), granulocytes, Recognizes the human CD162 cell surface glycoprotein |
| Purification method: |
Purified IgG |
| Form/Appearance: |
0, 0, 09% sodium azide, 1% BSA, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Antibodies in liquid form can be shipped and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol has to added and the vial must be stored at -20°, C, Lyophilized antibodies may be transported at ambient temperature and stored for short terms at +4 degrees Celsius and at -20 for long term storage |
| Tested applications:: |
Flow Cytometry (FC/FACS), IHC - Frozen), Western Blot (WB), Immunohistochemistry (IHC - Paraffin |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
10 (PL2)] (IgG1) SELPLG / PSGL-1 / CD162, 8, 12, Monoclonal [ 5D8 |
| Short name: |
10 (PL2)] (IgG1) SELPLG / PSGL-1 / CD162 Antibody, 8, 12, Mouse Monoclonal [clone 5D8 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens selectin P ligand / PSGL-1 / CD162 (Antibody to), 10 (PL2)] (IgG1) to H, 8, 12, Mouse monoclonal [clonality 5D8 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD162 and CLA and PSGL-1 and PSGL1, Plasma membranes, SELPLG and IDBG-55469 and ENSG00000110876 and 6404, SELPLG and IDBG-635588 and ENSBTAG00000031851 and 617434, Selplg and IDBG-191890 and ENSMUSG00000048163 and 20345, protein binding, this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007596 and blood coagulation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0050900 and leukocyte migration and biological process this GO :0050901 and leukocyte tethering or rolling and biological process this GO :0050902 and leukocyte adhesive activation and biological process this GO :0071354 and cellular response to interleukin-6 and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, selectin P ligand |
| Identity: |
10722 |
| Gene: |
SELPLG |
More about : SELPLG |
| Long gene name: |
selectin P ligand |
| Synonyms: |
PSGL-1 CD162 |
| Locus: |
12q24, 11 |
| Discovery year: |
1995-01-31 |
| Entrez gene record: |
6404 |
| Pubmed identfication: |
7505206 |
| Classification: |
Endogenous ligands CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000169411 |