| Also known as: |
SELPLG / PSGL-1 / CD162 |
| Other names: |
CD_antigen: CD162, P-selectin glycoprotein ligand 1, P-selectin glycoprotein ligand 1, Selectin P ligand, cutaneous lymphocyte-associated associated antigen, selectin P ligand, P-selectin glycoprotein ligand 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SELPLG |
| Gene name synonims: |
CD162, PSGL-1 |
| Other gene names: |
CD162, CLA, PSGL-1, PSGL-1, PSGL1, SELPLG, SELPLG |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
TC2 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD162 is present on the most peripheral blood T lymphocytes, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 220 kD type I integral membrane protein expressed as disulfide-linked homodimer (sialomucin family), granulocytes, it is also expressed on a subpopulation of B lymphocytes and CD34+ bone marrow cells, monocytes, The antibody TC2 reacts with CD162 |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
15 mM sodium azide, pH 7, 4, PBS |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ TC2] (IgG1) SELPLG / PSGL-1 / CD162 |
| Short name: |
Mouse Monoclonal [clone TC2] (IgG1) SELPLG / PSGL-1 / CD162 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens selectin P ligand / PSGL-1 / CD162 (Antibody to), Mouse monoclonal [clonality TC2] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD162 and CLA and PSGL-1 and PSGL1, Plasma membranes, SELPLG and IDBG-55469 and ENSG00000110876 and 6404, SELPLG and IDBG-635588 and ENSBTAG00000031851 and 617434, Selplg and IDBG-191890 and ENSMUSG00000048163 and 20345, protein binding, this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007596 and blood coagulation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0050900 and leukocyte migration and biological process this GO :0050901 and leukocyte tethering or rolling and biological process this GO :0050902 and leukocyte adhesive activation and biological process this GO :0071354 and cellular response to interleukin-6 and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, selectin P ligand |
| Identity: |
10722 |
| Gene: |
SELPLG |
More about : SELPLG |
| Long gene name: |
selectin P ligand |
| Synonyms: |
PSGL-1 CD162 |
| Locus: |
12q24, 11 |
| Discovery year: |
1995-01-31 |
| Entrez gene record: |
6404 |
| Pubmed identfication: |
7505206 |
| Classification: |
Endogenous ligands CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000169411 |