| Also known as: |
ICAM3 / CD50 |
| Other names: |
CD_antigen: CD50, CDw50, ICAM-3, ICAM-R, Intercellular adhesion molecule 3, intercellular adhesion molecule 3, intercellular adhesion molecule 3, intercellular adhesion molecule-3, intercellular adhesion molecule 3 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ICAM3 |
| Gene name synonims: |
CD50 |
| Other gene names: |
CD50, CDW50, ICAM-3, ICAM-R, ICAM3, ICAM3 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
MEM-04 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1), This particular antibody might cross react with speacies outside of the listed ones, a 120-130 kD type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells, it is negative on platelets and erythrocytes, Reacts with CD50 (ICAM-3) |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
0, approx, pH 7, 2 mm filter sterilized, 4, Azide free phosphate buffered saline (PBS) |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Flow Cytometry (FC/FACS), Functional Assay, Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ MEM-04] (IgG1) ICAM3 / CD50 |
| Short name: |
Mouse Monoclonal [clone MEM-04] (IgG1) ICAM3 / CD50 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens intercellular adhesion molecule 3 / CD50 (Antibody to), Mouse monoclonal [clonality MEM-04] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD50 and CDW50 and ICAM-R, ICAM3 and IDBG-27123 and ENSG00000076662 and 3385, ICAM3 and IDBG-643267 and ENSBTAG00000015742 and 281840, Plasma membranes, protein binding, this GO :0005102 and receptor binding and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0050776 and regulation of immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, intercellular adhesion molecule 3 |
| Identity: |
5346 |
| Gene: |
ICAM3 |
More about : ICAM3 |
| Long gene name: |
intercellular adhesion molecule 3 |
| Synonyms: |
CDW50 ICAM-R CD50 |
| Locus: |
19p13, 2 |
| Discovery year: |
1994-05-19 |
| Entrez gene record: |
3385 |
| Pubmed identfication: |
1448174 |
| Classification: |
CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180410 |