| Long name: |
ICAM3/CD50 Primary Polyclonal Antibody |
| Also known as: |
ICAM3/CD50 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ICAM3/CD50 |
| Specificity: |
This is a highly specific antibody against ICAM3/CD50 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD50 |
| Gene ID number: |
3385 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ICAM3 is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA1 in the initiation of the immune response, It functions not only as an adhesion molecule, N-glycosylated, Upon stimulation by a physiological stimulus it becomes rapidly and transiently phosphorylated on serine residues, and bind to the leukocyte adhesion LFA1 protein, but also as a potent signalling molecule, contain 2-9 immunoglobulin-like C2-type domains, glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains, All ICAM proteins are type I transmembrane glycoproteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD50, CDW 50, CDW50, ICAM 3, ICAM 3, ICAM R, ICAM-3, ICAMR, intercellular adhesion molecules-3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ICAM3/CD50 |
| Short name: |
ICAM3/CD50 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
intercellular adhesion molecule 3/CD50 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD50 and CDW50 and ICAM-R, ICAM3 and IDBG-27123 and ENSG00000076662 and 3385, ICAM3 and IDBG-643267 and ENSBTAG00000015742 and 281840, Plasma membranes, protein binding, this GO :0005102 and receptor binding and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0050776 and regulation of immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, intercellular adhesion molecule 3 |
| Identity: |
5346 |
| Gene: |
ICAM3 |
More about : ICAM3 |
| Long gene name: |
intercellular adhesion molecule 3 |
| Synonyms: |
CDW50 ICAM-R CD50 |
| Locus: |
19p13, 2 |
| Discovery year: |
1994-05-19 |
| Entrez gene record: |
3385 |
| Pubmed identfication: |
1448174 |
| Classification: |
CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180410 |