| Long name: |
ALEXA FLUOR 350 Conjugated, P53(wt-p53) (D2F7) Monoclonal Antibody |
| Also known as: |
Anti-P53wt-p53 MAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Mouse (Mus musculus) |
| Target Antigen: |
P53wt-p53 |
| Specificity: |
This is a highly specific antibody against P53wt-p53 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Monoclonal |
| Clone: |
D2F7 |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human P53(wt-p53) |
| Gene ID Number: |
7157 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
20937277), Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms, DNA binding, DNA repair, Feb 2013], Mutations in this gene are associated with a variety of human cancers, The encoded protein responds to diverse cellular stresses to regulate expression of target genes, [provided by RefSeq, and oligomerization domains, apoptosis, including hereditary cancers such as Li-Fraumeni syndrome, or changes in metabolism, senescence, thereby inducing cell cycle arrest, This gene encodes a tumor suppressor protein containing transcriptional activation |
| Purification: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
p53 LFS1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
P53(wt-p53) (D2F7) Monoclonal |
| Short name: |
P53(wt-p53) (D2F7) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, P53(wt-p53) (D2F7) monoclonal (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11998 |
| Gene: |
TP53 |
More about : TP53 |
| Long gene name: |
tumor protein p53 |
| Synonyms name: |
Li-Fraumeni syndrome |
| Locus: |
17p13, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
AF307851 |
| Entrez gene record: |
7157 |
| Pubmed identfication: |
6396087 3456488 2047879 |
| RefSeq identity: |
NM_000546 |
| Havana BLAST/BLAT: |
OTTHUMG00000162125 |
| Locus Specific Databases: |
IARC TP53 Mutation Database p53 UMD TP53 mutation database Database of Germline p53 Mutations MUTP53LOAD, Mutant p53 Loss Of Activity Database LRG_321 |