| Long name: |
P53(wt-p53) (D2F7) Monoclonal Antibody |
| Also known as: |
P53(wt-p53) (D2F7) Monoclonal Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
P53wt-p53 |
| Specificity: |
This is a highly specific antibody against P53wt-p53 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
D2F7 |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human P53(wt-p53) |
| Gene ID number: |
7157 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
20937277), Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms, DNA binding, DNA repair, Feb 2013], Mutations in this gene are associated with a variety of human cancers, The encoded protein responds to diverse cellular stresses to regulate expression of target genes, [provided by RefSeq, and oligomerization domains, apoptosis, including hereditary cancers such as Li-Fraumeni syndrome, or changes in metabolism, senescence, thereby inducing cell cycle arrest, This gene encodes a tumor suppressor protein containing transcriptional activation |
| Purification method: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Antigen NY-CO-13, Cellular tumor antigen p53, Cys 51 Stop, HGNC11998, LFS1, P53_HUMAN, Phosphoprotein p53, TP53, TP53, TRP53, Transformation related protein 53, Tumor protein p53, Tumour Protein p53, Wtp53, p53, p53 Cellular Tumor Antigen, p53 Tumor Suppressor, Widespread p53 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
P53(wt-p53) (D2F7) Monoclonal |
| Short name: |
P53(wt-p53) (D2F7) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
P53(wt-p53) (D2F7) monoclonal (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11998 |
| Gene: |
TP53 |
More about : TP53 |
| Long gene name: |
tumor protein p53 |
| Synonyms: |
p53 LFS1 |
| Synonyms name: |
Li-Fraumeni syndrome |
| Locus: |
17p13, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
AF307851 |
| Entrez gene record: |
7157 |
| Pubmed identfication: |
6396087 3456488 2047879 |
| RefSeq identity: |
NM_000546 |
| Havana BLAST/BLAT: |
OTTHUMG00000162125 |
| Locus Specific Databases: |
IARC TP53 Mutation Database p53 UMD TP53 mutation database Database of Germline p53 Mutations MUTP53LOAD, Mutant p53 Loss Of Activity Database LRG_321 |