| Also known as: |
NCK1 / NCK |
| Other names: |
Cytoplasmic protein NCK1, NCK adaptor protein 1, NCK adaptor protein 1, NCK tyrosine kinase, Nck-1, SH2/SH3 adaptor protein NCK-alpha, SH2/SH3 adaptor protein NCK-alpha, cytoplasmic protein NCK1, melanoma NCK protein, non-catalytic region of tyrosine kinase, cytoplasmic protein NCK1 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
NCK1 |
| Gene name synonims: |
NCK |
| Other gene names: |
NCK, NCK, NCK1, NCKalpha, Nck-1, nck-1, NCK1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Clone: |
11D10 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Ammonium sulfate precipitation |
| Form/Appearance: |
0, 0, and 50% glycerol, 01% BSA, 03% sodium azide, 15M NaCl, HEPES with 0 |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 11D10] (IgG1, k) NCK1 / NCK |
| Short name: |
Mouse Monoclonal [clone 11D10] (IgG1, k) NCK1 / NCK Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens NCK adaptor protein 1 / NCK (Antibody to), Mouse monoclonal [clonality 11D10] (IgG1, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
NCK and nck-1 and NCKalpha, NCK1 and IDBG-58017 and ENSG00000158092 and 4690, NCK1 and IDBG-638662 and ENSBTAG00000018427 and 536154, Nck1 and IDBG-193200 and ENSMUSG00000032475 and 17973, nuclei, receptor tyrosine kinase binding, this GO :0004860 and protein kinase inhibitor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006417 and regulation of translation and biological process this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0007015 and actin filament organization and biological process this GO :0007172 and signal complex assembly and biological process this GO :0007411 and axon guidance and biological process this GO :0008093 and cytoskeletal adaptor activity and molecular function this GO :0012506 and vesicle membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0019887 and protein kinase regulator activity and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0030032 and lamellipodium assembly and biological process this GO :0030159 and receptor signaling complex scaffold activity and molecular function this GO :0030838 and positive regulation of actin filament polymerization and biological process this GO :0030971 and receptor tyrosine kinase binding and molecular function this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042110 and T cell activation and biological process this GO :0045087 and innate immune response and biological process this GO :0045859 and regulation of protein kinase activity and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051707 and response to other organism and biological process this GO :0060548 and negative regulation of cell death and biological process, this GO :0004860 : protein kinase inhibitor activity, this GO :0004860 : protein kinase inhibitor activity and also this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0008093 : cytoskeletal adaptor activity and also this GO :0019887 : protein kinase regulator activity and also this GO :0019904 : protein domain specific binding and also this GO :0030159 : receptor signaling complex scaffold activity and also this GO :0030971 : receptor tyrosine kinase binding, this GO :0005102 : receptor binding, this GO :0005515 : protein binding, this GO :0008093 : cytoskeletal adaptor activity, this GO :0019887 : protein kinase regulator activity, this GO :0019904 : protein domain specific binding, this GO :0030159 : receptor signaling complex scaffold activity, this GO :0030971 : receptor tyrosine kinase binding, NCK adaptor protein 1 |
| Identity: |
7664 |
| Gene: |
NCK1 |
More about : NCK1 |
| Long gene name: |
NCK adaptor protein 1 |
| Synonyms gene: |
NCK |
| Synonyms: |
NCKalpha |
| Locus: |
3q22, 3 |
| Discovery year: |
1998-11-04 |
| GenBank acession: |
X17576 |
| Entrez gene record: |
4690 |
| Pubmed identfication: |
7806213 9737977 |
| RefSeq identity: |
NM_006153 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000159781 |