| Also known as: |
HSPB1 / HSP27 |
| Other names: |
28 kDa heat shock protein, 28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, HSP 27, HSP 27, Heat shock 27 kDa protein, Heat shock protein beta-1, SRP27, Stress-responsive protein 27, epididymis secretory protein Li 102, estrogen-regulated 24 kDa protein, heat shock 27 kDa protein, heat shock 27kD protein 1, heat shock 27kDa protein 1, heat shock protein beta-1, stress-responsive protein 27, heat shock protein beta-1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
HSPB1 |
| Gene name synonims: |
HSP27 |
| Other gene names: |
CMT2F, HEL-S-102, HMN2B, HS, HSP 27, HSP27, HSP27, HSP28, HSP28, HSPB1, Hsp25, HspB1, SRP27, SRP27, 76067, HSPB1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
2A5 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, pH 7, 1% sodium azide, 4, PBS |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 2A5] (IgG1) HSPB1 / HSP27 |
| Short name: |
Mouse Monoclonal [clone 2A5] (IgG1) HSPB1 / HSP27 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens heat shock 27kDa protein 1 / HSP27 (Antibody to), Mouse monoclonal [clonality 2A5] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CMT2F and HEL-S-102 and HMN2B and HS, HSPB1 and IDBG-23058 and ENSG00000106211 and 3315, HSPB1 and IDBG-640144 and ENSBTAG00000011969 and 516099, Hspb1 and IDBG-204151 and ENSMUSG00000004951 and 15507, nuclei, poly(A) RNA binding, this GO :0000502 and proteasome complex and cellular component this GO :0001895 and retina homeostasis and biological process this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005819 and spindle and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006446 and regulation of translational initiation and biological process this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006928 and cellular component movement and biological process this GO :0006986 and response to unfolded protein and biological process this GO :0008219 and cell death and biological process this GO :0008426 and protein kinase C inhibitor activity and molecular function this GO :0009615 and response to virus and biological process this GO :0010467 and gene expression and biological process this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030018 and Z disc and cellular component this GO :0032731 and positive regulation of interleukin-1 beta production and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035924 and cellular response to vascular endothelial growth factor stimulus and biological process this GO :0038033 and positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway and biological process this GO :0042535 and positive regulation of tumor necrosis factor biosynthetic process and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043122 and regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043130 and ubiquitin binding and molecular function this GO :0043292 and contractile fiber and cellular component this GO :0043536 and positive regulation of blood vessel endothelial cell migration and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071901 and negative regulation of protein serine/threonine kinase activity and biological process this GO :1902176 and negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway and biological process this GO :2001028 and positive regulation of endothelial cell chemotaxis and biological process this GO :2001234 and negative regulation of apoptotic signaling pathway and biological process, this GO :0005080 : protein kinase C binding, this GO :0005080 : protein kinase C binding and also this GO :0005515 : protein binding and also this GO :0008426 : protein kinase C inhibitor activity and also this GO :0019901 : protein kinase binding and also this GO :0042802 : identical protein binding and also this GO :0043130 : ubiquitin binding and also this GO :0044822 : poly(A) RNA binding, this GO :0005515 : protein binding, this GO :0008426 : protein kinase C inhibitor activity, this GO :0019901 : protein kinase binding, this GO :0042802 : identical protein binding, this GO :0043130 : ubiquitin binding, this GO :0044822 : poly(A) RNA binding, 76067 and Hsp25 and HSP27 and HSP28 and SRP27, heat shock 27kDa protein 1 |
| Identity: |
5246 |
| Gene: |
HSPB1 |
More about : HSPB1 |
| Long gene name: |
heat shock protein family B (small) member 1 |
| Synonyms gene name: |
heat shock 27kD protein 1 heat shock 27kDa protein 1 |
| Synonyms: |
HSP27 HSP28 Hs, 76067 Hsp25 CMT2F |
| Locus: |
7q11, 23 |
| Discovery year: |
1991-07-09 |
| GenBank acession: |
X54079 |
| Entrez gene record: |
3315 |
| Pubmed identfication: |
2243808 9344682 |
| Classification: |
Small heat shock proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000023228 |
| Locus Specific Databases: |
Inherited Peripheral Neuropathies Mutation Database LRG_248 |