| Also known as: |
PINK1 |
| Other names: |
BRPK, PTEN induced putative kinase 1, PTEN-induced putative kinase protein 1, PTEN-induced putative kinase protein 1, Serine/threonine-protein kinase PINK1, mitochondrial, mitochondrial, mitochondrial, protein kinase BRPK, serine/threonine-protein kinase PINK1, serine/threonine-protein kinase PINK1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
PINK1 |
| Other gene names: |
BRPK, N/A, PARK6, PINK1, PINK1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
38CT20, 5, 8 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The antibody has not been tested for suitability in IHC with mouse samples, This particular antibody might cross react with speacies outside of the listed ones, Cross-reactivity with mouse has been confirmed in Western blot only |
| Purification method: |
Ascites |
| Form/Appearance: |
0, Sourced in Ascites, 09% sodium azide, Ascites |
| Storage and shipping: |
For long term storage For optimal long term storage, for up to 6 months, the antibody should be kept at -20 degrees Celsius, Maintain refrigerated at the antibodys should be kept in the range of 1-7 degrees Celsius |
| Tested applications:: |
Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
5] (IgG1) PINK1, 8, Monoclonal [ 38CT20 |
| Short name: |
5] (IgG1) PINK1 Antibody, 8, Mouse Monoclonal [clone 38CT20 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens phosphatase and tensin homolog induced putative kinase 1 (Antibody to), 5] (IgG1) to H, 8, Mouse monoclonal [clonality 38CT20 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
PINK1 and IDBG-645657 and ENSBTAG00000006084 and 510683, PINK1 and IDBG-92922 and ENSG00000158828 and 65018, Pink1 and IDBG-199773 and ENSMUSG00000028756 and 68943, dopaminergic and biological process this GO :0033603 and positive regulation of dopamine secretion and biological process this GO :0033605 and positive regulation of catecholamine secretion and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043254 and regulation of protein complex assembly and biological process this GO :0043523 and regulation of neuron apoptotic process and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0055131 and C3HC4-type RING finger domain binding and molecular function this GO :0090200 and positive regulation of release of cytochrome c from mitochondria and biological process this GO :0097237 and cellular response to toxic substance and biological process this GO :1902176 and negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway and biological process, nuclei, this GO :0000287 and magnesium ion binding and molecular function this GO :0000422 and mitochondrion degradation and biological process this GO :0000785 and chromatin and cellular component this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005758 and mitochondrial intermembrane space and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006950 and response to stress and biological process this GO :0008219 and cell death and biological process this GO :0010857 and calcium-dependent protein kinase activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016301 and kinase activity and molecular function this GO :0016567 and protein ubiquitination and biological process this GO :0016772 and transferase activity, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0010857 : calcium-dependent protein kinase activity and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0010857 : calcium-dependent protein kinase activity, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, this GO :0031625 : ubiquitin protein ligase binding, this GO :0055131 : C3HC4-type RING finger domain binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0055131 : C3HC4-type RING finger domain binding, transferring phosphorus-containing groups and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0031396 and regulation of protein ubiquitination and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032226 and positive regulation of synaptic transmission, PTEN induced putative kinase 1 |
| Identity: |
14581 |
| Gene: |
PINK1 |
More about : PINK1 |
| Long gene name: |
PTEN induced putative kinase 1 |
| Synonyms gene: |
PARK6 |
| Synonyms gene name: |
Parkinson disease (autosomal recessive) 6 |
| Locus: |
1p36, 12 |
| Discovery year: |
2001-02-08 |
| GenBank acession: |
AB053323 |
| Entrez gene record: |
65018 |
| Pubmed identfication: |
11494141 15349860 |
| RefSeq identity: |
NM_032409 |
| Classification: |
Parkinson disease associated genes |
| Havana BLAST/BLAT: |
OTTHUMG00000002841 |
| Locus Specific Databases: |
Parkinson', s disease Mutation Database |