| Also known as: |
TLR8 |
| Other names: |
CD_antigen: CD288, Toll-like receptor 8, toll-like receptor 8, toll-like receptor 8, toll-like receptor 8 isoform 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
TLR8 |
| Other gene names: |
CD288, N/A, TLR8, TLR8 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG, k |
| Clone: |
44C143 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
It will cross-react with mouse TLR8, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, within amino acids 750-850, A KLH-conjugated synthetic peptide of human TLR8 |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, 0, Sourced in TCS, 05% BSA, 05% sodium azide, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, Each murine monoclonal anibody has his own affinity specific for the clone, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, Monoclonals of this antigen are available in different clones, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 44C143] , k) TLR8 |
| Short name: |
Mouse Monoclonal [clone 44C143] (IgG, k) TLR8 Antibody |
| Technique: |
IgGs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens toll-like receptor 8 (Antibody to), Mouse monoclonal [clonality 44C143] (Immunoglobulin G, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Plasma membranes, TLR8 and IDBG-44288 and ENSG00000101916 and 51311, Tlr8 and IDBG-185523 and ENSMUSG00000040522 and 170744, drug binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001774 and microglial cell activation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0003677 and DNA binding and molecular function this GO :0003723 and RNA binding and molecular function this GO :0003725 and double-stranded RNA binding and molecular function this GO :0003727 and single-stranded RNA binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0008144 and drug binding and molecular function this GO :0009615 and response to virus and biological process this GO :0010008 and endosome membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016064 and immunoglobulin mediated immune response and biological process this GO :0034158 and toll-like receptor 8 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0036020 and endolysosome membrane and cellular component this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045089 and positive regulation of innate immune response and biological process this GO :0045356 and positive regulation of interferon-alpha biosynthetic process and biological process this GO :0045359 and positive regulation of interferon-beta biosynthetic process and biological process this GO :0045416 and positive regulation of interleukin-8 biosynthetic process and biological process this GO :0050707 and regulation of cytokine secretion and biological process this GO :0051607 and defense response to virus and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003723 : RNA binding and also this GO :0003725 : double-stranded RNA binding and also this GO :0003727 : single-stranded RNA binding and also this GO :0004872 : receptor activity and also this GO :0005515 : protein binding and also this GO :0008144 : drug binding, this GO :0003723 : RNA binding, this GO :0003725 : double-stranded RNA binding, this GO :0003727 : single-stranded RNA binding, this GO :0004872 : receptor activity, this GO :0005515 : protein binding, this GO :0008144 : drug binding, toll-like receptor 8 |
| Identity: |
15632 |
| Gene: |
TLR8 |
More about : TLR8 |
| Long gene name: |
toll like receptor 8 |
| Synonyms gene name: |
toll-like receptor 8 |
| Synonyms: |
CD288 |
| Locus: |
Xp22, 2 |
| Discovery year: |
2001-04-27 |
| GenBank acession: |
AF246971 |
| Entrez gene record: |
51311 |
| Pubmed identfication: |
11022119 |
| RefSeq identity: |
NM_016610 |
| Classification: |
CD molecules Toll like receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000021145 |
| Locus Specific Databases: |
Mental Retardation database |