| Also known as: |
CD59 |
| Other names: |
1F5 antigen, 1F5 antigen, 20 kDa homologous restriction factor, 20 kDa homologous restriction factor, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16, CD59 glycoprotein, CD59 glycoprotein, CD59 molecule, CD_antigen: CD59, EJ16, EJ30, EL32 and G344), HRF-20, HRF20, Ly-6-like protein, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MEM43 antigen, MIRL, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin, T cell-activating protein, complement regulatory protein, human leukocyte antigen MIC11, lymphocytic antigen CD59/MEM43, membrane attack complex (MAC) inhibition factor, membrane attack complex inhibition factor, membrane inhibitor of reactive lysis, protectin, surface anitgen recognized by monoclonal antibody 16, 3A5, 3A5, CD59 glycoprotein preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD59 |
| Other gene names: |
16, 1F5, CD59, EJ16, EJ30, EL32, G344, HRF-20, HRF-20, HRF20, HRF20, MAC-IP, MAC-IP, MACIF, MACIF, MEM43, MIC11, MIC11, MIN1, MIN1, MIN2, MIN2, MIN3, MIN3, MIRL, MIRL, MSK21, MSK21, p18-20, 3A5, CD59 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
MEM-43 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Thymocytes and T lymphocytes |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
15 mM sodium azide, approx, pH 7, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ MEM-43] (IgG2a) CD59 |
| Short name: |
Mouse Monoclonal [clone MEM-43] (IgG2a) CD59 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
complement regulatory protein (Antibody to), sapiens CD59 molecule, Mouse monoclonal [clonality MEM-43] (IgG2a) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
16, CD59 and IDBG-38813 and ENSG00000085063 and 966, CD59 and IDBG-636427 and ENSBTAG00000002302 and 505574, Extracellular, complement regulatory protein, protein binding, this GO :0001775 and cell activation and biological process this GO :0001848 and complement binding and molecular function this GO :0001971 and negative regulation of activation of membrane attack complex and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0030449 and regulation of complement activation and biological process this GO :0031362 and anchored component of external side of plasma membrane and cellular component this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042383 and sarcolemma and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043218 and compact myelin and cellular component this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001848 : complement binding, this GO :0001848 : complement binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, 3A5 and 1F5 and EJ16 and EJ30 and EL32 and G344 and HRF-20 and HRF20 and MAC-IP and MACIF and MEM43 and MIC11 and MIN1 and MIN2 and MIN3 and MIRL and MSK21 and p18-20, CD59 molecule |
| Identity: |
1689 |
| Gene: |
CD59 |
More about : CD59 |
| Long gene name: |
CD59 molecule |
| Synonyms gene: |
MIC11 MIN1 MSK21 MIN2 MIN3 |
| Synonyms gene name: |
CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16, EJ16, EJ30, EL32 and G344) CD59 antigen, complement regulatory protein , complement regulatory protein CD59 molecule, 3A5 |
| Synonyms: |
16, 3A5 EJ16 EJ30 EL32 G344 p18-20 |
| Locus: |
11p13 |
| Discovery year: |
1989-06-30 |
| Entrez gene record: |
966 |
| Pubmed identfication: |
7691713 |
| RefSeq identity: |
NM_203329 |
| Classification: |
Complement system CD molecules LY6/PLAUR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166270 |
| Locus Specific Databases: |
CD59base: Mutation registry for CD59 deficiency LRG_41 |