| Alternative name 1: |
Biotin, Clone: MEM 43, Hematopoietic and non-Hematopoietic Cell, MAC Inhibitor, Mab anti-Human, gp18-20, CD59 |
| Alternative name 2: |
Biotin, Clone: MEM 43, Hematopoietic and non-Hematopoietic Cell, MAC Inhibitor, Mab antibody-Human, gp18-20, CD59 |
| Alternative name 3: |
Biotin, Clone: MEM 43, Hematopoietic and non-Hematopoietic Cell, MAC Inhibitor, Mab antibody-Homo sapiens, gp18-20, CD59 |
| Alternative name 4: |
anti-CD59 MAC Inhibitor Hematopoietic and non-Hematopoietic Cell gp18-20 Clone: MEM 43 |
| Alternative name 5: |
CD59 MAC Inhibitor Hematopoietic and non-Hematopoietic Cell gp18-20 Clone: MEM 43 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, 6, Biotin conjugates can be detected by horseradish peroxidase, Homo sapiens sapiens), humans , ssp |
| Conjugation: |
Biotinylated |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Hematopoietic non-Hematopoietic gp18-20, MAC Inhibitor, MEM 43, Monoclonal, CD59 |
| Short name: |
Clone: MEM 43, Hematopoietic non-Hematopoietic Cell, MAC Inhibitor, Mouse Monoclonal antibody-, gp18-20, CD59 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Label: |
Biotin |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
Hematopoietic and non-Hematopoietic cellular, MAC suppressor, Mouse monoclonal (Antibody to)-H, biotinilated, clonality: MEM 43, complement regulatory protein, gp18-20, sapiens, CD59 molecule |
| Alternative technique: |
murine |
| Alternative to gene target: |
16, CD59 and IDBG-38813 and ENSG00000085063 and 966, CD59 and IDBG-636427 and ENSBTAG00000002302 and 505574, Extracellular, complement regulatory protein, protein binding, this GO :0001775 and cell activation and biological process this GO :0001848 and complement binding and molecular function this GO :0001971 and negative regulation of activation of membrane attack complex and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0030449 and regulation of complement activation and biological process this GO :0031362 and anchored component of external side of plasma membrane and cellular component this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042383 and sarcolemma and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043218 and compact myelin and cellular component this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001848 : complement binding, this GO :0001848 : complement binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, 3A5 and 1F5 and EJ16 and EJ30 and EL32 and G344 and HRF-20 and HRF20 and MAC-IP and MACIF and MEM43 and MIC11 and MIN1 and MIN2 and MIN3 and MIRL and MSK21 and p18-20, CD59 molecule |
| Identity: |
1689 |
| Gene: |
CD59 |
More about : CD59 |
| Long gene name: |
CD59 molecule |
| Synonyms gene: |
MIC11 MIN1 MSK21 MIN2 MIN3 |
| Synonyms gene name: |
CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16, EJ16, EJ30, EL32 and G344) CD59 antigen, complement regulatory protein , complement regulatory protein CD59 molecule, 3A5 |
| Synonyms: |
16, 3A5 EJ16 EJ30 EL32 G344 p18-20 |
| Locus: |
11p13 |
| Discovery year: |
1989-06-30 |
| Entrez gene record: |
966 |
| Pubmed identfication: |
7691713 |
| RefSeq identity: |
NM_203329 |
| Classification: |
Complement system CD molecules LY6/PLAUR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166270 |
| Locus Specific Databases: |
CD59base: Mutation registry for CD59 deficiency LRG_41 |