| known also as: |
Anti-Rabbit Polyclonal (IgG) to Human TNFRSF10B / Killer / DR5 |
| known also as: |
Rabbit PAb (IgG) to Human TNFRSF10B / Killer / DR5 |
| known also as: |
Lapin Polyclonal (IgG) to Homo sapiens TNFRSF10B / Killer / DR5 |
| known also as: |
TNFRSF10B / Killer / DR5 |
| known also as: |
CD262, CD262 antigen, Cytotoxic TRAIL receptor-2, DR5, DR5, Death receptor 5, Fas-like protein, Human TNFRSF10B, KILLER, Killer, TNFRSF10B, TRAIL receptor 2, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9, Anti-TNFRSF10B / Killer / DR5 Antibody (aa388-407) IHC-plus |
| Other names: |
CD_antigen: CD262, Death receptor 5, Fas-like protein, TNF receptor superfamily member 10b, TNF-related apoptosis-inducing ligand receptor 2, TNF-related apoptosis-inducing ligand receptor 2, TRAIL receptor 2, TRAIL-R2, Tumor necrosis factor receptor superfamily member 10B, apoptosis inducing protein TRICK2A/2B, apoptosis inducing receptor TRAIL-R2, cytotoxic TRAIL receptor-2, death domain containing receptor for TRAIL/Apo-2L, death receptor 5, member 10b, p53-regulated DNA damage-inducible cell death receptor(killer), tumor necrosis factor receptor superfamily, tumor necrosis factor receptor superfamily member 10B, tumor necrosis factor receptor-like protein ZTNFR9, tumor necrosis factor receptor superfamily member 10B isoform 1 |
| Gene name: |
TNFRSF10B |
| Other gene names: |
CD262, DR5, DR5, KILLER, KILLER, KILLER/DR5, TNFRSF10B, TRAIL receptor 2, TRAIL-R2, TRAIL-R2, TRAILR2, TRAILR2, TRICK2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9, ZTNFR9, TNFRSF10B |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
The same sequence is found in isoform 1 at amino acids 417-436, A peptide corresponding to amino acids 388 to 407 (isoform 2) of human DR5 precursor |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, 0, 05% BSA, 05% sodium azide, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
avoid freeze thaw cycles, long term aliquot and store productone should be stored at -20 degrees Celsius, Short term Store productone at +4 degrees Celsius |
| Tested for:: |
Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| About: |
2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Gene target: |
PAb TNFRSF10B / Killer / DR5 |
| Short name: |
PAb (IgG) TNFRSF10B / Killer / DR5 |
| Technique: |
IgGs, IgG |
| Isotype: |
IgG |
| Species: |
Humans, Human |
| Alternative name: |
member 10b / Killer / DR5, sapiens tumor necrosis factor receptor superfamily, polyclonal (Immunoglobulin G) to H |
| Alternative technique: |
immunoglobulins |
| Alternative to gene target: |
CD262 and DR5 and KILLER and KILLER/DR5 and TRAIL-R2 and TRAILR2 and TRICK2 and TRICK2A and TRICK2B and TRICKB and ZTNFR9, Plasma membranes, TNFRSF10B and IDBG-11376 and ENSG00000120889 and 8795, TRAIL binding, member 10b, this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007250 and activation of NF-kappaB-inducing kinase activity and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0034976 and response to endoplasmic reticulum stress and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045569 and TRAIL binding and molecular function this GO :0070059 and intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :2001239 and regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005515 : protein binding and also this GO :0045569 : TRAIL binding, this GO :0005515 : protein binding, this GO :0045569 : TRAIL binding, tumor necrosis factor receptor superfamily |
| Identity: |
11905 |
| Gene: |
TNFRSF10B |
More about : TNFRSF10B |
| Long gene name: |
TNF receptor superfamily member 10b |
| Synonyms gene name: |
member 10b , tumor necrosis factor receptor superfamily |
| Synonyms: |
DR5 KILLER TRICK2A TRAIL-R2 TRICKB CD262 |
| Locus: |
8p21, 3 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
AF012628 |
| Entrez gene record: |
8795 |
| Pubmed identfication: |
9285725 9311998 |
| RefSeq identity: |
NM_147187 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000097826 |