| Also known as: |
RIG-I |
| Other names: |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58, DEAD box protein 58, DEAD box protein 58, DEAD-box protein 58, DEAD/H box polypeptide RIG-I, Probable ATP-dependent RNA helicase DDX58, RIG-1, RIG-1, RIG-I-like receptor 1, RIG-I-like receptor 1, RLR-1, Retinoic acid-inducible gene 1 protein, Retinoic acid-inducible gene I protein, probable ATP-dependent RNA helicase DDX58, retinoic acid-inducible gene 1 protein, retinoic acid-inducible gene I protein, retinoic acid-inducible gene-I, probable ATP-dependent RNA helicase DDX58 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
RIG-I |
| Other gene names: |
6430573D20Rik, C330021E21, Ddx58, RIG-1, RIG-I, RIG-I, RLR-1, RLR-1, Ddx58 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
SS1A |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
RIG-I is a receptor found in the cytoplasm that recognises viral RNA from replicating viruses in infected cells, RIG-I is essential for the production of interferons in response to RNA viruses and as such play a key role in innate immunity, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Upon activation with intracellular RNA, a cascade is triggered resulting in the activation of NF-kappa-B, also known as DEAD-box protein 58, and the eventual induction of antiviral cytokines such as IFN-beta and RANTES, or RIG-I, RIG-I This item recognises mouse Retinoic acid-inducible gene 1 protein |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
RIG-I |
| Short name: |
RAT ANTI MOUSE RIG-I Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE RIG-I (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19102 |
| Gene: |
DDX58 |
More about : DDX58 |
| Long gene name: |
DExD/H-box helicase 58 |
| Synonyms gene name: |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| Synonyms: |
RIG-I FLJ13599 DKFZp434J1111 |
| Synonyms name: |
RNA helicase RIG-I retinoic acid inducible gene I |
| Locus: |
9p21, 1 |
| Discovery year: |
2004-05-10 |
| GenBank acession: |
AF038963 |
| Entrez gene record: |
23586 |
| Pubmed identfication: |
21690088 |
| RefSeq identity: |
NM_014314 |
| Classification: |
DEAD-box helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000019746 |