| Also known as: |
ESTROGEN RECEPTOR BETA 2 |
| Other names: |
Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2, estrogen nuclear receptor beta variant a, estrogen nuclear receptor beta variant b, estrogen receptor 2 (ER beta), estrogen receptor beta, estrogen receptor beta 4, nuclear receptor subfamily 3 group A member 2, estrogen receptor beta isoform 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ER-BETA, ER-beta, ESR-BETA, ESR2, ESRB, ESTRB, ESTRB, Erb, NR3A2, NR3A2, ESR2 |
| Gene name synonims: |
ER-BETA, ER-beta, ESR-BETA, ESR2, ESRB, ESTRB, ESTRB, Erb, NR3A2, NR3A2, ESR2 |
| Other gene names: |
ER-BETA, ER-beta, ESR-BETA, ESR2, ESRB, ESTRB, ESTRB, Erb, NR3A2, NR3A2, ESR2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
57/3 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Approximately 75% to 80% of breast tumors have estrogen and/or progesterone receptors, No cross-reactivity is seen with estrogen receptor beta 1 isoform, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_ The detection of estrogen (ER) and progesterone (PR) receptors using immunohistochemical staining of formal fixed paraffin embedded (FFPE) tissue, and the presence of these receptors helps determine both the patient's prognosis and the effectiveness of hormonal therapy, expressed in cell nuclei of a range of human tissues including the ovary, has gradually replaced ligand binding assays (LBA), placenta, testis and vas deferens, to become the most common method for the determination of the ER/PR status of breast tumors, ESTROGEN RECEPTOR BETA 2 Clone 57/3 recognises the estrogen receptor beta 2 isoform |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunohistology - Paraffin (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
ESTROGEN RECEPTOR BETA 2 |
| Short name: |
MOUSE Anti-HUMAN ESTROGEN RECEPTOR BETA 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens ESTROGEN RECEPTOR b 2 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
3468 |
| Gene: |
ESR2 |
More about : ESR2 |
| Long gene name: |
estrogen receptor 2 |
| Synonyms gene name: |
estrogen receptor 2 (ER beta) |
| Synonyms: |
NR3A2 Erb |
| Synonyms name: |
ER beta |
| Locus: |
14q23, 2-q23, 3 |
| Discovery year: |
1997-01-17 |
| GenBank acession: |
X99101 |
| Entrez gene record: |
2100 |
| Pubmed identfication: |
8769313 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000141306 |