| Also known as: |
AID |
| Other names: |
Activation-induced cytidine deaminase, Cytidine aminohydrolase, activation-induced cytidine deaminase, activation-induced cytidine deaminase, cytidine aminohydrolase, integrated into Burkitt's lymphoma cell line Ramos, activation-induced cytidine deaminase |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
AID |
| Other gene names: |
AICDA, AID, AID, ARP2, CDA2, HIGM2, AICDA |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
2D3 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Studies suggest that AID is selectively expressed by germinal centre (GC) B cells and B cell-derived lymphomas, a 24kDa RNA-editing enzyme essential for the initiation of immunoglobulin class switch recombination (CSR), and that a deficiency in AID is responsible for the autosomal recessive form of the immunodeficient condition Hyper-IgM syndrome, somatic hypermutation (SHM) and gene conversion (GC), AID This item specifically recognizes human AID (Activation-induced cytidine deaminase) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
ELISA (EIA), Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
AID |
| Short name: |
MOUSE Anti-HUMAN AID Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens AID (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
13203 |
| Gene: |
AICDA |
More about : AICDA |
| Long gene name: |
activation induced cytidine deaminase |
| Synonyms gene name: |
activation-induced cytidine deaminase |
| Synonyms: |
HIGM2 CDA2 ARP2 AID |
| Locus: |
12p13, 31 |
| Discovery year: |
2000-09-19 |
| GenBank acession: |
AB040430 |
| Entrez gene record: |
57379 |
| RefSeq identity: |
NM_020661 |
| Classification: |
Apolipoprotein B mRNA editing enzyme catalytic subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000168676 |
| Locus Specific Databases: |
AICDA base: Mutation registry for Aid deficiency LRG_17 |