| known also as: |
Anti-RABBIT ANTI AID (C-TERMINAL) |
| known also as: |
RABBIT ANTI AID (C-TERMINAL) |
| known also as: |
Lapin ANTI AID (C-TERMINAL) |
| known also as: |
AID |
| Other names: |
Activation-induced cytidine deaminase, Cytidine aminohydrolase, activation-induced cytidine deaminase, activation-induced cytidine deaminase, cytidine aminohydrolase, integrated into Burkitt's lymphoma cell line Ramos, activation-induced cytidine deaminase |
| Gene name: |
AID |
| Other gene names: |
AICDA, AID, AID, ARP2, CDA2, HIGM2, AICDA |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
APOBEC-1, IgA or IgE isotypes, These genetic modification events take place within highly specialised B cell germinal centres, _x000D__x000D_Although the molecular mechanisms by which AID acts remain unclear, a 24kDa homologue of the RNA-editing cytidine deaminase enzyme, a growing number of studies reveal a requirement for AID during somatic hypermutation (SHM) and class switch recombination (CSR), during the final maturation stages of B cells, giving rise to high-affinity antibodies which use CSR to switch from IgM to IgG, AID This item recognises an epitope within the C-terminal region (CT) of Activation-induced cytidine deaminase (AID), _x000D_ |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
AID |
| Short name: |
Anti-AID (C-TERMINAL) |
| Alternative name: |
antibody to-AID (C-TERMINAL) |
| Identity: |
13203 |
| Gene: |
AICDA |
More about : AICDA |
| Long gene name: |
activation induced cytidine deaminase |
| Synonyms gene name: |
activation-induced cytidine deaminase |
| Synonyms: |
HIGM2 CDA2 ARP2 AID |
| Locus: |
12p13, 31 |
| Discovery year: |
2000-09-19 |
| GenBank acession: |
AB040430 |
| Entrez gene record: |
57379 |
| RefSeq identity: |
NM_020661 |
| Classification: |
Apolipoprotein B mRNA editing enzyme catalytic subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000168676 |
| Locus Specific Databases: |
AICDA base: Mutation registry for Aid deficiency LRG_17 |