| known also as: |
Anti-Rabbit Polyclonal (IgG) to Human HIF1A / HIF1 Alpha |
| known also as: |
Rabbit PAb (IgG) to Human HIF1A / HIF1 Alpha |
| known also as: |
Lapin Polyclonal (IgG) to Homo sapiens HIF1A / HIF1 Alpha |
| known also as: |
HIF1A / HIF1 Alpha |
| known also as: |
ARNT interacting protein, ARNT-interacting protein, BHLHe78, HIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1 Alpha, HIF1 Alpha, HIF1-ALPHA, HIF1A, Human HIF1A, Hypoxia-inducible factor1alpha, MOP1, Member of PAS protein 1, Member of PAS superfamily 1, PASD8, Anti-HIF1A / HIF1 Alpha Antibody (C-Terminus) IHC-plus |
| Other names: |
ARNT interacting protein, ARNT-interacting protein, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, Class E basic helix-loop-helix protein 78, HIF-1-alpha, Hypoxia-inducible factor 1-alpha, Member of PAS protein 1, PAS domain-containing protein 8, PAS domain-containing protein 8, alpha subunit (basic helix-loop-helix transcription factor), alpha subunit (basic helix-loop-helix transcription factor), bHLHe78, basic-helix-loop-helix-PAS protein MOP1, class E basic helix-loop-helix protein 78, hypoxia inducible factor 1, hypoxia-inducible factor 1, hypoxia-inducible factor 1 alpha isoform I, hypoxia-inducible factor 1-alpha, hypoxia-inducible factor1alpha, member of PAS protein 1, member of PAS superfamily 1, 3, hypoxia-inducible factor 1-alpha isoform 1 |
| Gene name: |
HIF1A |
| Other gene names: |
BHLHE78, HIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, HIF1-alpha, HIF1A, MOP1, MOP1, PASD8, PASD8, bHLHe78, bHLHe78, HIF1A |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Bovine, Chimpanzee, Dog, Gibbon, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Orangutan, Pig, Rat <, /b>, Bat, Chicken (at least 90% immunogen sequence identity), Predicted Reactivity: <, b> |
| Specificity and cross-reactivity: |
HIF-1 alpha amino acids (SRNLLQGEELLRALDQVN) |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
TBS |
| Storage and shipping: |
Avoid repeat freeze-thaw cycles, Short term: +Store productone at +4 degrees Celsius, Long term: Store productone at -20 degrees Celsius |
| Tested for:: |
Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
- or alpha protein sometimes glycoprotein present in blood, The PAb (IgG) HIF1A / HIF1 Alpha Antibody is a &alpha |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Gene target: |
PAb HIF1A / HIF1 Alpha |
| Short name: |
PAb (IgG) HIF1A / HIF1 Alpha Antibody |
| Technique: |
IgGs, antibodies against human proteins, antibodies for, Antibody |
| Isotype: |
IgG |
| Species: |
Humans, Human |
| Alternative name: |
a subunit (basic helix-loop-helix transcription factor) / HIF1 a (Antibody to), sapiens hypoxia inducible factor 1, polyclonal (Immunoglobulin G) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006879 and cellular iron ion homeostasis and biological process this GO :0007165 and signal transduction and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007595 and lactation and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008542 and visual learning and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0010573 and vascular endothelial growth factor production and biological process this GO :0010575 and positive regulation vascular endothelial growth factor production and biological process this GO :0010634 and positive regulation of epithelial cell migration and biological process this GO :0010870 and positive regulation of receptor biosynthetic process and biological process this GO :0014850 and response to muscle activity and biological process this GO :0019896 and axon transport of mitochondrion and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0021502 and neural fold elevation formation and biological process this GO :0021987 and cerebral cortex development and biological process this GO :0030154 and cell differentiation and biological process this GO :0030502 and negative regulation of bone mineralization and biological process this GO :0030949 and positive regulation of vascular endothelial growth factor receptor signaling pathway and biological process this GO :0031514 and motile cilium and cellular component this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032007 and negative regulation of TOR signaling and biological process this GO :0032364 and oxygen homeostasis and biological process this GO :0032722 and positive regulation of chemokine production and biological process this GO :0032909 and regulation of transforming growth factor beta2 production and biological process this GO :0032963 and collagen metabolic process and biological process this GO :0035035 and histone acetyltransferase binding and molecular function this GO :0035162 and embryonic hemopoiesis and biological process this GO :0035257 and nuclear hormone receptor binding and molecular function this GO :0035774 and positive regulation of insulin secretion involved in cellular response to glucose stimulus and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042541 and hemoglobin biosynthetic process and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0042789 and mRNA transcription from RNA polymerase II promoter and biological process this GO :0042826 and histone deacetylase binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043619 and regulation of transcription from RNA polymerase II promoter in response to oxidative stress and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045648 and positive regulation of erythrocyte differentiation and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0045821 and positive regulation of glycolytic process and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045926 and negative regulation of growth and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046716 and muscle cell cellular homeostasis and biological process this GO :0046886 and positive regulation of hormone biosynthetic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0048514 and blood vessel morphogenesis and biological process this GO :0048546 and digestive tract morphogenesis and biological process this GO :0050790 and regulation of catalytic activity and biological process this GO :0051000 and positive regulation of nitric-oxide synthase activity and biological process this GO :0051216 and cartilage development and biological process this GO :0051541 and elastin metabolic process and biological process this GO :0051879 and Hsp90 protein binding and molecular function this GO :0060574 and intestinal epithelial cell maturation and biological process this GO :0061030 and epithelial cell differentiation involved in mammary gland alveolus development and biological process this GO :0061298 and retina vasculature development in camera-type eye and biological process this GO :0061418 and regulation of transcription from RNA polymerase II promoter in response to hypoxia and biological process this GO :0061419 and positive regulation of transcription from RNA polymerase II promoter in response to hypoxia and biological process this GO :0070101 and positive regulation of chemokine-mediated signaling pathway and biological process this GO :0070243 and regulation of thymocyte apoptotic process and biological process this GO :0070244 and negative regulation of thymocyte apoptotic process and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0071542 and dopaminergic neuron differentiation and biological process this GO :2001054 and negative regulation of mesenchymal cell apoptotic process and biological process, HIF1A and IDBG-646757 and ENSBTAG00000020935 and 281814, HIF1A and IDBG-8510 and ENSG00000100644 and 3091, Hif1a and IDBG-148620 and ENSMUSG00000021109 and 15251, Hsp90 protein binding, alpha subunit (basic helix-loop-helix transcription factor), bHLHe78 and HIF-1A and HIF-1alpha and HIF1 and HIF1-ALPHA and MOP1 and PASD8, nuclei, this GO :0000989 and transcription factor binding transcription factor activity and molecular function this GO :0001076 and RNA polymerase II transcription factor binding transcription factor activity and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001525 and angiogenesis and biological process this GO :0001568 and blood vessel development and biological process this GO :0001666 and response to hypoxia and biological process this GO :0001755 and neural crest cell migration and biological process this GO :0001837 and epithelial to mesenchymal transition and biological process this GO :0001892 and embryonic placenta development and biological process this GO :0001922 and B-1 B cell homeostasis and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0001944 and vasculature development and biological process this GO :0001947 and heart looping and biological process this GO :0002052 and positive regulation of neuroblast proliferation and biological process this GO :0002248 and connective tissue replacement involved in inflammatory response wound healing and biological process this GO :0003151 and outflow tract morphogenesis and biological process this GO :0003208 and cardiac ventricle morphogenesis and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006089 and lactate metabolic process and biological process this GO :0006110 and regulation of glycolytic process and biological process this GO :0006351 and transcription, this GO :0000989 : transcription factor binding transcription factor activity, this GO :0000989 : transcription factor binding transcription factor activity and also this GO :0001076 : RNA polymerase II transcription factor binding transcription factor activity and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0004871 : signal transducer activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0035035 : histone acetyltransferase binding and also this GO :0035257 : nuclear hormone receptor binding and also this GO :0042826 : histone deacetylase binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0046983 : protein dimerization activity and also this GO :0051879 : Hsp90 protein binding, this GO :0001076 : RNA polymerase II transcription factor binding transcription factor activity, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0004871 : signal transducer activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0035035 : histone acetyltransferase binding, this GO :0035257 : nuclear hormone receptor binding, this GO :0042826 : histone deacetylase binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046982 : protein heterodimerization activity, this GO :0046983 : protein dimerization activity, this GO :0051879 : Hsp90 protein binding, hypoxia inducible factor 1 |
| Identity: |
4910 |
| Gene: |
HIF1A |
More about : HIF1A |
| Long gene name: |
hypoxia inducible factor 1 alpha subunit |
| Synonyms gene name: |
alpha subunit (basic helix-loop-helix transcription factor) , hypoxia inducible factor 1 |
| Synonyms: |
MOP1 HIF-1alpha PASD8 HIF1 bHLHe78 |
| Locus: |
14q23, 2 |
| Discovery year: |
1995-03-27 |
| GenBank acession: |
U22431 |
| Entrez gene record: |
3091 |
| Pubmed identfication: |
8786149 9079689 |
| RefSeq identity: |
NM_001530 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000140344 |