| Long name: |
HRP Conjugated, BCL-2 (1A5) Monoclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
BCL-2 |
| Specificity: |
This is a highly specific antibody against BCL-2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Monoclonal |
| Clone: |
1A5 |
| Concentration: |
1ug per 1ul |
| Source: |
Recombinant protein fragment (1-220 amino acids range) of human Bcl-2 |
| Gene ID number: |
596 |
| Swiss Prot: |
P10415 |
| Tested applications: |
WB |
| Recommended dilutions: |
WB(1:100-1000) |
| Crossreactivity: |
Mouse, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Appears to function in a feedback loop system with caspases, Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1), May attenuate inflammation by impairing NLRP1-inflammasome activation, Regulates cell death by controlling the mitochondrial membrane permeability, hence CASP1 activation and IL1B release, Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells |
| Purification method: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
Bcl-2 PPP1R50 |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
BCL-2 (1A5) Conjugated |
| Short name: |
Conjugated, BCL-2 (1A5) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, BCL-2 (1A5) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
990 |
| Gene: |
BCL2 |
More about : BCL2 |
| Long gene name: |
BCL2, apoptosis regulator |
| Synonyms gene name: |
B-cell CLL/lymphoma 2 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 50 |
| Locus: |
18q21, 33 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M14745 |
| Entrez gene record: |
596 |
| RefSeq identity: |
NM_000633 NM_000657 |
| Classification: |
Protein phosphatase 1 regulatory subunits BCL2 family |
| Havana BLAST/BLAT: |
OTTHUMG00000132791 |
| Locus Specific Databases: |
LRG_1113 |