| Also known as: |
CD273 |
| Other names: |
Butyrophilin B7-DC, PD-1 ligand 2, PDCD1 ligand 2, Programmed cell death 1 ligand 2, butyrophilin B7-DC, butyrophilin-like protein, programmed cell death 1 ligand 2, programmed cell death 1 ligand 2, programmed death ligand 2, programmed cell death 1 ligand 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD273 |
| Other gene names: |
B7-DC, B7-DC, B7dc, Btdc, Btdc, Cd273, F730015O22Rik, PD-1 ligand 2, PD-L2, PD-L2, PDCD1 ligand 2, Pdcd1lg2, Pdl2, Programmed death ligand 2, Pdcd1lg2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
TY25 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor, CD273 has been identified as a ligand for PD-1(CD279), GM-CSF or IL-4, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production, The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), This particular antibody might cross react with speacies outside of the listed ones, a 42kD member of the B7 family, along with another B7 family member B7-H1 (CD274), and DCs and macrophages that have been stimulated with interferon gamma, or programmed death ligand-2 (PD-L2), otherwise known as B7-dendritic cell (B7-DC), CD273 This item recognises mouse CD273 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunohistology - Frozen (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD273 |
| Short name: |
RAT ANTI MOUSE CD273 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD273 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18731 |
| Gene: |
PDCD1LG2 |
More about : PDCD1LG2 |
| Long gene name: |
programmed cell death 1 ligand 2 |
| Synonyms: |
PD-L2 Btdc PDL2 bA574F11, 2 CD273 B7-DC |
| Synonyms name: |
B7 dendritic cell molecule |
| Locus: |
9p24, 1 |
| Discovery year: |
2003-11-14 |
| GenBank acession: |
AF344424 |
| Entrez gene record: |
80380 |
| Pubmed identfication: |
11224527 |
| RefSeq identity: |
NM_025239 |
| Classification: |
Endogenous ligands CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000019504 |