| Also known as: |
CD273 |
| Other names: |
B7 dendritic cell molecule, B7-DC, Butyrophilin B7-DC, PD-1 ligand 2, PD-1-ligand 2, PDCD1 ligand 2, Programmed cell death 1 ligand 2, butyrophilin B7-DC, programmed cell death 1 ligand 2, programmed cell death 1 ligand 2, programmed death ligand 2, programmed cell death 1 ligand 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD273 |
| Other gene names: |
B7-DC, B7DC, B7DC, Btdc, CD273, CD273, PD-1 ligand 2, PD-L2, PD-L2, PDCD1 ligand 2, PDCD1L2, PDCD1L2, PDCD1LG2, PDL2, PDL2, Programmed death ligand 2, bA574F11, 2, PDCD1LG2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
MIH14 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD273 is a 42kD member of the immunoglobulin receptor superfamily, CD273 is primarily expressed on dendritic cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD273 functions to inhibit T-cell proliferation by blocking cell cycle progression and cytokine production, also known as B7-DC and Programmed Death Ligand 2 (PD-L2), and is a ligand for CD279 (PD-1), and is particularly important in the maintenance of self tolerance, and its expression can be induced on inflammatory macrophages when activated by interleukin 4 or Th2 cells, CD273 This item detects human CD273 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunohistology - Frozen (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD273 |
| Short name: |
MOUSE Anti-HUMAN CD273 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD273 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
18731 |
| Gene: |
PDCD1LG2 |
More about : PDCD1LG2 |
| Long gene name: |
programmed cell death 1 ligand 2 |
| Synonyms: |
PD-L2 Btdc PDL2 bA574F11, 2 CD273 B7-DC |
| Synonyms name: |
B7 dendritic cell molecule |
| Locus: |
9p24, 1 |
| Discovery year: |
2003-11-14 |
| GenBank acession: |
AF344424 |
| Entrez gene record: |
80380 |
| Pubmed identfication: |
11224527 |
| RefSeq identity: |
NM_025239 |
| Classification: |
Endogenous ligands CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000019504 |